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The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

Author

Listed:
  • Abed AlFatah Mansour

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ohad Gafni

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Leehee Weinberger

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Asaf Zviran

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Muneef Ayyash

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Yoach Rais

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Vladislav Krupalnik

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Mirie Zerbib

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Daniela Amann-Zalcenstein

    (Weizmann Institute of Science, Rehovot 76100, Israel
    Weizmann Institute of Science, Rehovot 76100, Israel)

  • Itay Maza

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Shay Geula

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Sergey Viukov

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Liad Holtzman

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ariel Pribluda

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Eli Canaani

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Shirley Horn-Saban

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ido Amit

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Noa Novershtern

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Jacob H. Hanna

    (Weizmann Institute of Science, Rehovot 76100, Israel)

Abstract

The H3K27 demethylase Utx is reported to be a critical regulator for the initiation of somatic and germ cell reprogramming.

Suggested Citation

  • Abed AlFatah Mansour & Ohad Gafni & Leehee Weinberger & Asaf Zviran & Muneef Ayyash & Yoach Rais & Vladislav Krupalnik & Mirie Zerbib & Daniela Amann-Zalcenstein & Itay Maza & Shay Geula & Sergey Viuk, 2012. "The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming," Nature, Nature, vol. 488(7411), pages 409-413, August.
    • Handle: RePEc:nat:nature:v:488:y:2012:i:7411:d:10.1038_nature11272
    DOI: 10.1038/nature11272
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    Cited by:

    1. Daniel F. Kaemena & Masahito Yoshihara & Meryam Beniazza & James Ashmore & Suling Zhao & Mårten Bertenstam & Victor Olariu & Shintaro Katayama & Keisuke Okita & Simon R. Tomlinson & Kosuke Yusa & Keis, 2023. "B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Mengwen Hu & Yu-Han Yeh & Yasuhisa Munakata & Hironori Abe & Akihiko Sakashita & So Maezawa & Miguel Vidal & Haruhiko Koseki & Neil Hunter & Richard M. Schultz & Satoshi H. Namekawa, 2022. "PRC1-mediated epigenetic programming is required to generate the ovarian reserve," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    3. Chuan Gao & Ian C McDowell & Shiwen Zhao & Christopher D Brown & Barbara E Engelhardt, 2016. "Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering," PLOS Computational Biology, Public Library of Science, vol. 12(7), pages 1-39, July.

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