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Recurrent network activity drives striatal synaptogenesis

Author

Listed:
  • Yevgenia Kozorovitskiy

    (Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Ave, Boston, Massachusetts 02115, USA)

  • Arpiar Saunders

    (Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Ave, Boston, Massachusetts 02115, USA)

  • Caroline A. Johnson

    (Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Ave, Boston, Massachusetts 02115, USA)

  • Bradford B. Lowell

    (Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA)

  • Bernardo L. Sabatini

    (Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Ave, Boston, Massachusetts 02115, USA)

Abstract

Neurotransmitter release and activity are modulated in the striatum of mice to demonstrate that the balance of activity within the two antagonistic, inhibitory pathways co-mingled in this nucleus regulates excitatory innervation of the basal ganglia during development.

Suggested Citation

  • Yevgenia Kozorovitskiy & Arpiar Saunders & Caroline A. Johnson & Bradford B. Lowell & Bernardo L. Sabatini, 2012. "Recurrent network activity drives striatal synaptogenesis," Nature, Nature, vol. 485(7400), pages 646-650, May.
    • Handle: RePEc:nat:nature:v:485:y:2012:i:7400:d:10.1038_nature11052
    DOI: 10.1038/nature11052
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    Cited by:

    1. Yixin Wu & Mingzheng Wu & Abraham Vázquez-Guardado & Joohee Kim & Xin Zhang & Raudel Avila & Jin-Tae Kim & Yujun Deng & Yongjoon Yu & Sarah Melzer & Yun Bai & Hyoseo Yoon & Lingzi Meng & Yi Zhang & He, 2022. "Wireless multi-lateral optofluidic microsystems for real-time programmable optogenetics and photopharmacology," Nature Communications, Nature, vol. 13(1), pages 1-15, December.

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