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Spatial partitioning of the regulatory landscape of the X-inactivation centre

Author

Listed:
  • Elphège P. Nora

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

  • Bryan R. Lajoie

    (Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester)

  • Edda G. Schulz

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

  • Luca Giorgetti

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

  • Ikuhiro Okamoto

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

  • Nicolas Servant

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    INSERM U900, Paris, F-75248 France
    Mines ParisTech, Fontainebleau, F-77300 France)

  • Tristan Piolot

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

  • Nynke L. van Berkum

    (Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester)

  • Johannes Meisig

    (Institute of Pathology, Charité–Universitätsmedizin, 10117 Berlin, and Institute of Theoretical Biology Humboldt Universität, 10115 Berlin, Germany)

  • John Sedat

    (University of California San Francisco)

  • Joost Gribnau

    (Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands)

  • Emmanuel Barillot

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    INSERM U900, Paris, F-75248 France
    Mines ParisTech, Fontainebleau, F-77300 France)

  • Nils Blüthgen

    (Institute of Pathology, Charité–Universitätsmedizin, 10117 Berlin, and Institute of Theoretical Biology Humboldt Universität, 10115 Berlin, Germany)

  • Job Dekker

    (Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester)

  • Edith Heard

    (Institut Curie, 26 rue d'Ulm, Paris F-75248, France
    CNRS UMR3215, Paris F-75248, France
    INSERM U934, Paris F-75248, France)

Abstract

High-order chromatin folding in topologically associating domains has a critical role in proper long-range transcriptional control around the Xist locus, and presumably throughout the genome.

Suggested Citation

  • Elphège P. Nora & Bryan R. Lajoie & Edda G. Schulz & Luca Giorgetti & Ikuhiro Okamoto & Nicolas Servant & Tristan Piolot & Nynke L. van Berkum & Johannes Meisig & John Sedat & Joost Gribnau & Emmanuel, 2012. "Spatial partitioning of the regulatory landscape of the X-inactivation centre," Nature, Nature, vol. 485(7398), pages 381-385, May.
    • Handle: RePEc:nat:nature:v:485:y:2012:i:7398:d:10.1038_nature11049
    DOI: 10.1038/nature11049
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