IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v484y2012i7395d10.1038_nature11042.html
   My bibliography  Save this article

Infection regulates pro-resolving mediators that lower antibiotic requirements

Author

Listed:
  • Nan Chiang

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

  • Gabrielle Fredman

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

  • Fredrik Bäckhed

    (Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory, University of Gothenburg, SE-413 45 Gothenburg, Sweden)

  • Sungwhan F. Oh

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

  • Thad Vickery

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

  • Birgitta A. Schmidt

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

  • Charles N. Serhan

    (Center for Experimental Therapeutics and Reperfusion Injury, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School)

Abstract

Resolvins and protectins are anti-inflammatory and pro-resolving lipid mediators that are shown to resolve infections, and their administration lowers required doses of antibiotics and shortens infections.

Suggested Citation

  • Nan Chiang & Gabrielle Fredman & Fredrik Bäckhed & Sungwhan F. Oh & Thad Vickery & Birgitta A. Schmidt & Charles N. Serhan, 2012. "Infection regulates pro-resolving mediators that lower antibiotic requirements," Nature, Nature, vol. 484(7395), pages 524-528, April.
    • Handle: RePEc:nat:nature:v:484:y:2012:i:7395:d:10.1038_nature11042
    DOI: 10.1038/nature11042
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature11042
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature11042?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:484:y:2012:i:7395:d:10.1038_nature11042. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.