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Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

Author

Listed:
  • F.-Xabier Contreras

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany)

  • Andreas M. Ernst

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany)

  • Per Haberkant

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany
    Present address: Cell Biology and Biophysics Unit EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany.)

  • Patrik Björkholm

    (Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden
    Stockholm Bioinformatics Center, Science for Life Laboratory Stockholm University, Box 1031, SE-171 21 Solna, Sweden)

  • Erik Lindahl

    (Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden
    Theoretical & Computational Biophysics, Royal Institute of Technology, AlbaNova University Centre, SE-106 91 Stockholm, Sweden)

  • Başak Gönen

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany)

  • Christian Tischer

    (ALMF, EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany)

  • Arne Elofsson

    (Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden
    Stockholm Bioinformatics Center, Science for Life Laboratory Stockholm University, Box 1031, SE-171 21 Solna, Sweden)

  • Gunnar von Heijne

    (Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden
    Stockholm Bioinformatics Center, Science for Life Laboratory Stockholm University, Box 1031, SE-171 21 Solna, Sweden)

  • Christoph Thiele

    (LIMES Life and Medical Sciences Institute, Carl-Troll-Strasse 31, 53115 Bonn, Germany)

  • Rainer Pepperkok

    (ALMF, EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany)

  • Felix Wieland

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany)

  • Britta Brügger

    (Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany)

Abstract

A sphingomyelin-binding motif is identified in the membrane-spanning domain of p24, a COPI machinery protein.

Suggested Citation

  • F.-Xabier Contreras & Andreas M. Ernst & Per Haberkant & Patrik Björkholm & Erik Lindahl & Başak Gönen & Christian Tischer & Arne Elofsson & Gunnar von Heijne & Christoph Thiele & Rainer Pepperkok & F, 2012. "Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain," Nature, Nature, vol. 481(7382), pages 525-529, January.
  • Handle: RePEc:nat:nature:v:481:y:2012:i:7382:d:10.1038_nature10742
    DOI: 10.1038/nature10742
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