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TRIM5 does double duty

Author

Listed:
  • Christopher Aiken

    (Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.)

  • Sebastian Joyce

    (Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.)

Abstract

TRIM5 proteins limit retroviral infection by targeting the viral coat. It now seems that these proteins can also serve as pattern-recognition receptors, which initiate cellular innate immune responses. See Letter p.361

Suggested Citation

  • Christopher Aiken & Sebastian Joyce, 2011. "TRIM5 does double duty," Nature, Nature, vol. 472(7343), pages 305-306, April.
    • Handle: RePEc:nat:nature:v:472:y:2011:i:7343:d:10.1038_472305a
    DOI: 10.1038/472305a
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