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Targeting early infection to prevent HIV-1 mucosal transmission

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  • Ashley T. Haase

    (University of Minnesota)

Abstract

HIV: transmission failure The goal of preventing sexual mucosal transmission of HIV/AIDS, the principal route of acquisition, remains a priority if the pandemic is to be contained and HIV ultimately eradicated. In a review focused on pathogenesis in tissues relevant to mucosal transmission, particularly in the well characterized simian immunodeficiency virus rhesus macaque model, Ashley Haase argues that prevention strategies should target the earliest stage of infection — using both vaccines and microbicides.

Suggested Citation

  • Ashley T. Haase, 2010. "Targeting early infection to prevent HIV-1 mucosal transmission," Nature, Nature, vol. 464(7286), pages 217-223, March.
    • Handle: RePEc:nat:nature:v:464:y:2010:i:7286:d:10.1038_nature08757
    DOI: 10.1038/nature08757
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    Cited by:

    1. Suzanna C Francis & Yanwen Hou & Kathy Baisley & Janneke van de Wijgert & Deborah Watson-Jones & Trong T Ao & Carolina Herrera & Kaballa Maganja & Aura Andreasen & Saidi Kapiga & Gary R Coulton & Rich, 2016. "Immune Activation in the Female Genital Tract: Expression Profiles of Soluble Proteins in Women at High Risk for HIV Infection," PLOS ONE, Public Library of Science, vol. 11(1), pages 1-28, January.

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