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Three birds with one stone

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  • Franck Toledo

    (Franck Toledo and Boris Bardot are in the Genetics of Tumor Suppression Group, Institut Curie, 75248 Paris Cedex 05, France, and at the Université Pierre et Marie Curie Paris 06, Paris, France. franck.toledo@curie.fr)

  • Boris Bardot

    (Franck Toledo and Boris Bardot are in the Genetics of Tumor Suppression Group, Institut Curie, 75248 Paris Cedex 05, France, and at the Université Pierre et Marie Curie Paris 06, Paris, France. franck.toledo@curie.fr)

Abstract

The core domain of the p53 protein has been found to affect microRNA processing — its third known antitumour activity. Most cancerous p53 mutations affect this domain and may abolish all tumour-suppressor functions.

Suggested Citation

  • Franck Toledo & Boris Bardot, 2009. "Three birds with one stone," Nature, Nature, vol. 460(7254), pages 466-467, July.
    • Handle: RePEc:nat:nature:v:460:y:2009:i:7254:d:10.1038_460466a
    DOI: 10.1038/460466a
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