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Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases

Author

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  • Yasuto Murayama

    (International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan)

  • Yumiko Kurokawa

    (International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan)

  • Kouta Mayanagi

    (Nagahama Institute of Bio-Science and Technology, 1266, Tamura, Nagahama, Shiga 526-0829, Japan
    BIRD, JST, 1266, Tamura, Nagahama, Shiga 526-0829, Japan)

  • Hiroshi Iwasaki

    (International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan)

Abstract

Although the bacterial RecA protein has been previously described to facilitate reciprocal duplex DNA exchange, here the first eukaryotic proteins, yeast Rhp51 and human Rad51, are demonstrated to catalyse this process.

Suggested Citation

  • Yasuto Murayama & Yumiko Kurokawa & Kouta Mayanagi & Hiroshi Iwasaki, 2008. "Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases," Nature, Nature, vol. 451(7181), pages 1018-1021, February.
    • Handle: RePEc:nat:nature:v:451:y:2008:i:7181:d:10.1038_nature06609
    DOI: 10.1038/nature06609
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