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An essential role for a CD36-related receptor in pheromone detection in Drosophila

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  • Richard Benton

    (Laboratory of Neurogenetics and Behaviour, The Rockefeller University, 1230 York Avenue, Box 63, New York, New York 10065, USA
    Present addresses: Center for Integrative Genomics, Genopode Building, University of Lausanne, CH-1015 Lausanne, Switzerland (R.B.); Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA (K.S.V.).)

  • Kirsten S. Vannice

    (Laboratory of Neurogenetics and Behaviour, The Rockefeller University, 1230 York Avenue, Box 63, New York, New York 10065, USA
    Present addresses: Center for Integrative Genomics, Genopode Building, University of Lausanne, CH-1015 Lausanne, Switzerland (R.B.); Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA (K.S.V.).)

  • Leslie B. Vosshall

    (Laboratory of Neurogenetics and Behaviour, The Rockefeller University, 1230 York Avenue, Box 63, New York, New York 10065, USA)

Abstract

A molecule involved in pathogen recognition by the immune system has a homologue functioning in insect pheromone detection. These results suggest a unifying model whereby the protein CD 36 recognizes lipids (bacterial components or insect pheromones) and couples that to intracellular signalling in the immune or nervous systems.

Suggested Citation

  • Richard Benton & Kirsten S. Vannice & Leslie B. Vosshall, 2007. "An essential role for a CD36-related receptor in pheromone detection in Drosophila," Nature, Nature, vol. 450(7167), pages 289-293, November.
    • Handle: RePEc:nat:nature:v:450:y:2007:i:7167:d:10.1038_nature06328
    DOI: 10.1038/nature06328
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