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Caught in the traffic

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  • Aparna Lakkaraju

    (Aparna Lakkaraju and Enrique Rodriguez-Boulan are at the Margaret M. Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, New York 10021, USA. boulan@med.cornell.edu)

  • Enrique Rodriguez-Boulan

    (Aparna Lakkaraju and Enrique Rodriguez-Boulan are at the Margaret M. Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, New York 10021, USA. boulan@med.cornell.edu)

Abstract

In mice, deletion of the Rab8 protein disrupts organized molecular distribution to membranes of intestinal epithelial cells. Death by starvation follows, exactly as it does in humans with microvillus inclusion disease.

Suggested Citation

  • Aparna Lakkaraju & Enrique Rodriguez-Boulan, 2007. "Caught in the traffic," Nature, Nature, vol. 448(7151), pages 266-267, July.
  • Handle: RePEc:nat:nature:v:448:y:2007:i:7151:d:10.1038_448266a
    DOI: 10.1038/448266a
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