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A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis

Author

Listed:
  • Marcel Tawk

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK)

  • Claudio Araya

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK)

  • Dave A. Lyons

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
    Present addresses: Department of Developmental Biology, Stanford University School of Medicine, Beckman Center B300, 279 Campus Drive, Stanford, California 94305, USA (D.A.L.); Department of Academic and Student Affairs, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA (P.R.B).)

  • Alexander M. Reugels

    (Institut für Entwicklungsbiologie, Universität zu Köln, 50923 Köln, Germany)

  • Gemma C. Girdler

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK)

  • Philippa R. Bayley

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
    Present addresses: Department of Developmental Biology, Stanford University School of Medicine, Beckman Center B300, 279 Campus Drive, Stanford, California 94305, USA (D.A.L.); Department of Academic and Student Affairs, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA (P.R.B).)

  • David R. Hyde

    (University of Notre Dame, Notre Dame, Indiana 46556, USA)

  • Masazumi Tada

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK)

  • Jonathan D. W. Clarke

    (Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK)

Abstract

In the developing neural tube of the zebrafish, a newly discovered kind of cell division occurs that produces two daughter cells with mirror symmetry. Cells are polarized in mirror symmetry on either side of the neural midline, and Pard3, a protein known to be involved in polarized cell divisions, is deposited within the cleavage furrow of the midline.

Suggested Citation

  • Marcel Tawk & Claudio Araya & Dave A. Lyons & Alexander M. Reugels & Gemma C. Girdler & Philippa R. Bayley & David R. Hyde & Masazumi Tada & Jonathan D. W. Clarke, 2007. "A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis," Nature, Nature, vol. 446(7137), pages 797-800, April.
  • Handle: RePEc:nat:nature:v:446:y:2007:i:7137:d:10.1038_nature05722
    DOI: 10.1038/nature05722
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