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Evidence that mechanisms of fin development evolved in the midline of early vertebrates

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Listed:
  • Renata Freitas

    (Department of Zoology)

  • GuangJun Zhang

    (Department of Zoology)

  • Martin J. Cohn

    (Department of Zoology
    University of Florida)

Abstract

Fin Tuning The origin of paired limbs in vertebrates has been an abiding source of interest. A number of recently described fossils from the Lower Cambrian of China suggest that the major components of the fin skeleton were assembled first in the midline and appeared later in paired fins. A study of embryo development in sharks and lampreys shows that sharks' median fins develop from a continuous fin fold derived mainly from paraxial mesoderm and that lampreys -primitive vertebrates that lack paired limbs - have a similar pattern of median fin development. In addition, the expression of the Tbx18 gene, which specifies the anterior limit of the paired forelimbs, also delineates the boundaries of median fin outgrowth. Together these results provide good support for the palaeontological hypothesis that paired appendages evolved by co-opting the median fin developmental program.

Suggested Citation

  • Renata Freitas & GuangJun Zhang & Martin J. Cohn, 2006. "Evidence that mechanisms of fin development evolved in the midline of early vertebrates," Nature, Nature, vol. 442(7106), pages 1033-1037, August.
    • Handle: RePEc:nat:nature:v:442:y:2006:i:7106:d:10.1038_nature04984
    DOI: 10.1038/nature04984
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