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Mesodermal Wnt2b signalling positively regulates liver specification

Author

Listed:
  • Elke A. Ober

    (University of California
    The Ridgeway)

  • Heather Verkade

    (University of California
    Royal Melbourne Hospital)

  • Holly A. Field

    (University of California
    Novartis Institutes for BioMedical Research, Inc.)

  • Didier Y. R. Stainier

    (University of California)

Abstract

This paper describes the identification of the only single gene that is known to exclusively regulate liver specification, and shows that liver formation is regulated by inductive Wnt signals and crosstalk between the endoderm and mesoderm along the gut tube.

Suggested Citation

  • Elke A. Ober & Heather Verkade & Holly A. Field & Didier Y. R. Stainier, 2006. "Mesodermal Wnt2b signalling positively regulates liver specification," Nature, Nature, vol. 442(7103), pages 688-691, August.
    • Handle: RePEc:nat:nature:v:442:y:2006:i:7103:d:10.1038_nature04888
    DOI: 10.1038/nature04888
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    Cited by:

    1. Ravi N Kapadia & Michael J Zeidman & Sathyaprasad Burjonrappa & Sathyaprasad Burjonrappa, 2015. "Advanced Hepatoblastoma: A Review of Current Management Strategies," Advanced Research in Gastroenterology & Hepatology, Juniper Publishers Inc., vol. 1(1), pages 1-8, September.

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