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DNA sequence and analysis of human chromosome 8

Author

Listed:
  • Chad Nusbaum

    (Broad Institute of MIT and Harvard)

  • Tarjei S. Mikkelsen

    (Broad Institute of MIT and Harvard)

  • Michael C. Zody

    (Broad Institute of MIT and Harvard)

  • Shuichi Asakawa

    (Keio University School of Medicine)

  • Stefan Taudien

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Manuel Garber

    (Broad Institute of MIT and Harvard)

  • Chinnappa D. Kodira

    (Broad Institute of MIT and Harvard)

  • Mary G. Schueler

    (National Institutes of Health)

  • Atsushi Shimizu

    (Keio University School of Medicine)

  • Charles A. Whittaker

    (Broad Institute of MIT and Harvard
    MIT Center for Cancer Research)

  • Jean L. Chang

    (Broad Institute of MIT and Harvard)

  • Christina A. Cuomo

    (Broad Institute of MIT and Harvard)

  • Ken Dewar

    (Broad Institute of MIT and Harvard
    McGill University and Genome Quebec Innovation Centre)

  • Michael G. FitzGerald

    (Broad Institute of MIT and Harvard)

  • Xiaoping Yang

    (Broad Institute of MIT and Harvard)

  • Nicole R. Allen

    (Broad Institute of MIT and Harvard)

  • Scott Anderson

    (Broad Institute of MIT and Harvard)

  • Teruyo Asakawa

    (Keio University School of Medicine)

  • Karin Blechschmidt

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Toby Bloom

    (Broad Institute of MIT and Harvard)

  • Mark L. Borowsky

    (Broad Institute of MIT and Harvard)

  • Jonathan Butler

    (Broad Institute of MIT and Harvard)

  • April Cook

    (Broad Institute of MIT and Harvard)

  • Benjamin Corum

    (Broad Institute of MIT and Harvard)

  • Kurt DeArellano

    (Broad Institute of MIT and Harvard)

  • David DeCaprio

    (Broad Institute of MIT and Harvard)

  • Kathleen T. Dooley

    (Broad Institute of MIT and Harvard)

  • Lester Dorris

    (Broad Institute of MIT and Harvard)

  • Reinhard Engels

    (Broad Institute of MIT and Harvard)

  • Gernot Glöckner

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Nabil Hafez

    (Broad Institute of MIT and Harvard)

  • Daniel S. Hagopian

    (Broad Institute of MIT and Harvard)

  • Jennifer L. Hall

    (Broad Institute of MIT and Harvard)

  • Sabine K. Ishikawa

    (Keio University School of Medicine)

  • David B. Jaffe

    (Broad Institute of MIT and Harvard)

  • Asha Kamat

    (Broad Institute of MIT and Harvard)

  • Jun Kudoh

    (Keio University School of Medicine)

  • Rüdiger Lehmann

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Tashi Lokitsang

    (Broad Institute of MIT and Harvard)

  • Pendexter Macdonald

    (Broad Institute of MIT and Harvard)

  • John E. Major

    (Broad Institute of MIT and Harvard)

  • Charles D. Matthews

    (Broad Institute of MIT and Harvard)

  • Evan Mauceli

    (Broad Institute of MIT and Harvard)

  • Uwe Menzel

    (Genome Analysis, Institute of Molecular Biotechnology
    Uppsala University)

  • Atanas H. Mihalev

    (Broad Institute of MIT and Harvard)

  • Shinsei Minoshima

    (Keio University School of Medicine
    Hamamatsu University School of Medicine)

  • Yuji Murayama

    (Keio University School of Medicine)

  • Jerome W. Naylor

    (Broad Institute of MIT and Harvard)

  • Robert Nicol

    (Broad Institute of MIT and Harvard)

  • Cindy Nguyen

    (Broad Institute of MIT and Harvard)

  • Sinéad B. O'Leary

    (Broad Institute of MIT and Harvard)

  • Keith O'Neill

    (Broad Institute of MIT and Harvard)

  • Stephen C. J. Parker

    (Broad Institute of MIT and Harvard
    Boston University Bioinformatics and Systems Biology Program)

  • Andreas Polley

    (Genome Analysis, Institute of Molecular Biotechnology
    TraitGenetics GmbH)

  • Christina K. Raymond

    (Broad Institute of MIT and Harvard)

  • Kathrin Reichwald

    (Genome Analysis, Institute of Molecular Biotechnology
    University Clinic for Child and Adolescent Psychiatry, University of Duisburg-Essen)

  • Joseph Rodriguez

    (Broad Institute of MIT and Harvard)

  • Takashi Sasaki

    (Keio University School of Medicine)

  • Markus Schilhabel

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Roman Siddiqui

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Cherylyn L Smith

    (Broad Institute of MIT and Harvard)

  • Tam P. Sneddon

    (University College London, Wolfson House)

  • Jessica A. Talamas

    (Broad Institute of MIT and Harvard)

  • Pema Tenzin

    (Broad Institute of MIT and Harvard)

  • Kerri Topham

    (Broad Institute of MIT and Harvard)

  • Vijay Venkataraman

    (Broad Institute of MIT and Harvard)

  • Gaiping Wen

    (Genome Analysis, Institute of Molecular Biotechnology
    GSF-Forschungszentrum für Umwelt und Gesundheit)

  • Satoru Yamazaki

    (Keio University School of Medicine)

  • Sarah K. Young

    (Broad Institute of MIT and Harvard)

  • Qiandong Zeng

    (Broad Institute of MIT and Harvard)

  • Andrew R. Zimmer

    (Broad Institute of MIT and Harvard)

  • Andre Rosenthal

    (Genome Analysis, Institute of Molecular Biotechnology
    Signature Diagnostics AG)

  • Bruce W. Birren

    (Broad Institute of MIT and Harvard)

  • Matthias Platzer

    (Genome Analysis, Institute of Molecular Biotechnology)

  • Nobuyoshi Shimizu

    (Keio University School of Medicine)

  • Eric S. Lander

    (Broad Institute of MIT and Harvard)

Abstract

Chromosome in a hurry The finished sequence for human chromosome 8 is now published. It features a 15-megabase stretch that has a much greater mutation rate in hominids than the corresponding region in other mammals. Included in this region are genes influencing brain size and the immune system.

Suggested Citation

  • Chad Nusbaum & Tarjei S. Mikkelsen & Michael C. Zody & Shuichi Asakawa & Stefan Taudien & Manuel Garber & Chinnappa D. Kodira & Mary G. Schueler & Atsushi Shimizu & Charles A. Whittaker & Jean L. Chan, 2006. "DNA sequence and analysis of human chromosome 8," Nature, Nature, vol. 439(7074), pages 331-335, January.
    • Handle: RePEc:nat:nature:v:439:y:2006:i:7074:d:10.1038_nature04406
    DOI: 10.1038/nature04406
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