IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v436y2005i7050d10.1038_nature03812.html
   My bibliography  Save this article

The Lyme disease agent exploits a tick protein to infect the mammalian host

Author

Listed:
  • Nandhini Ramamoorthi

    (Sections of Rheumatology)

  • Sukanya Narasimhan

    (Sections of Rheumatology)

  • Utpal Pal

    (Sections of Rheumatology)

  • Fukai Bao

    (Sections of Rheumatology)

  • Xiaofeng F. Yang

    (University of Texas Southwestern Medical Center)

  • Durland Fish

    (Yale University School of Medicine)

  • Juan Anguita

    (University of North Carolina at Charlotte)

  • Michael V. Norgard

    (University of Texas Southwestern Medical Center)

  • Fred S. Kantor

    (Allergy and Immunology, Department of Internal Medicine)

  • John F. Anderson

    (Connecticut Agricultural Experiment Station)

  • Raymond A. Koski

    (L2 Diagnostics)

  • Erol Fikrig

    (Sections of Rheumatology
    Yale University School of Medicine)

Abstract

Can I borrow your coat? The Lyme disease spirochete has been found to take advantage of a tick protein in order to infect mice. The bacterium coats itself with a tick molecule that enables it to avoid host defences. If other vector-borne pathogens use this trick, it could provide a new target for therapeutics and vaccines.

Suggested Citation

  • Nandhini Ramamoorthi & Sukanya Narasimhan & Utpal Pal & Fukai Bao & Xiaofeng F. Yang & Durland Fish & Juan Anguita & Michael V. Norgard & Fred S. Kantor & John F. Anderson & Raymond A. Koski & Erol Fi, 2005. "The Lyme disease agent exploits a tick protein to infect the mammalian host," Nature, Nature, vol. 436(7050), pages 573-577, July.
    • Handle: RePEc:nat:nature:v:436:y:2005:i:7050:d:10.1038_nature03812
    DOI: 10.1038/nature03812
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature03812
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature03812?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Michael Pham & Jacob Underwood & Adela S. Oliva Chávez, 2021. "Changing the Recipe: Pathogen Directed Changes in Tick Saliva Components," IJERPH, MDPI, vol. 18(4), pages 1-20, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:436:y:2005:i:7050:d:10.1038_nature03812. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.