IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v432y2004i7018d10.1038_nature03030.html
   My bibliography  Save this article

A physical map of the chicken genome

Author

Listed:
  • John W. Wallis

    (Washington University School of Medicine, Campus Box 8501)

  • Jan Aerts

    (Wageningen University)

  • Martien A. M. Groenen

    (Wageningen University)

  • Richard P. M. A. Crooijmans

    (Wageningen University)

  • Dan Layman

    (Washington University School of Medicine, Campus Box 8501)

  • Tina A. Graves

    (Washington University School of Medicine, Campus Box 8501)

  • Debra E. Scheer

    (Washington University School of Medicine, Campus Box 8501)

  • Colin Kremitzki

    (Washington University School of Medicine, Campus Box 8501)

  • Mary J. Fedele

    (Washington University School of Medicine, Campus Box 8501)

  • Nancy K. Mudd

    (Washington University School of Medicine, Campus Box 8501)

  • Marco Cardenas

    (Washington University School of Medicine, Campus Box 8501)

  • Jamey Higginbotham

    (Washington University School of Medicine, Campus Box 8501)

  • Jason Carter

    (Washington University School of Medicine, Campus Box 8501)

  • Rebecca McGrane

    (Washington University School of Medicine, Campus Box 8501)

  • Tony Gaige

    (Washington University School of Medicine, Campus Box 8501)

  • Kelly Mead

    (Washington University School of Medicine, Campus Box 8501)

  • Jason Walker

    (Washington University School of Medicine, Campus Box 8501)

  • Derek Albracht

    (Washington University School of Medicine, Campus Box 8501)

  • Jonathan Davito

    (Washington University School of Medicine, Campus Box 8501)

  • Shiaw-Pyng Yang

    (Washington University School of Medicine, Campus Box 8501)

  • Shin Leong

    (Washington University School of Medicine, Campus Box 8501)

  • Asif Chinwalla

    (Washington University School of Medicine, Campus Box 8501)

  • Mandeep Sekhon

    (Washington University School of Medicine, Campus Box 8501)

  • Kristine Wylie

    (Washington University School of Medicine, Campus Box 8501)

  • Jerry Dodgson

    (Michigan State University)

  • Michael N. Romanov

    (Michigan State University)

  • Hans Cheng

    (Agricultural Research Service, USDA)

  • Pieter J. de Jong

    (Children's Hospital Oakland Research Institute)

  • Kazutoyo Osoegawa

    (Children's Hospital Oakland Research Institute)

  • Mikhail Nefedov

    (Children's Hospital Oakland Research Institute)

  • Hongbin Zhang

    (Texas A&M University)

  • John D. McPherson

    (Baylor College of Medicine, One Baylor Plaza Houston)

  • Martin Krzywinski

    (Genome Sciences Centre, British Columbia Cancer Agency)

  • Jacquie Schein

    (Genome Sciences Centre, British Columbia Cancer Agency)

  • LaDeana Hillier

    (Washington University School of Medicine, Campus Box 8501)

  • Elaine R. Mardis

    (Washington University School of Medicine, Campus Box 8501)

  • Richard K. Wilson

    (Washington University School of Medicine, Campus Box 8501)

  • Wesley C. Warren

    (Washington University School of Medicine, Campus Box 8501)

Abstract

Strategies for assembling large, complex genomes have evolved to include a combination of whole-genome shotgun sequencing and hierarchal map-assisted sequencing1,2. Whole-genome maps of all types can aid genome assemblies, generally starting with low-resolution cytogenetic maps and ending with the highest resolution of sequence. Fingerprint clone maps are based upon complete restriction enzyme digests of clones representative of the target genome, and ultimately comprise a near-contiguous path of clones across the genome. Such clone-based maps are used to validate sequence assembly order, supply long-range linking information for assembled sequences, anchor sequences to the genetic map and provide templates for closing gaps. Fingerprint maps are also a critical resource for subsequent functional genomic studies, because they provide a redundant and ordered sampling of the genome with clones3. In an accompanying paper4 we describe the draft genome sequence of the chicken, Gallus gallus, the first species sequenced that is both a model organism and a global food source. Here we present a clone-based physical map of the chicken genome at 20-fold coverage, containing 260 contigs of overlapping clones. This map represents approximately 91% of the chicken genome and enables identification of chicken clones aligned to positions in other sequenced genomes.

Suggested Citation

  • John W. Wallis & Jan Aerts & Martien A. M. Groenen & Richard P. M. A. Crooijmans & Dan Layman & Tina A. Graves & Debra E. Scheer & Colin Kremitzki & Mary J. Fedele & Nancy K. Mudd & Marco Cardenas & J, 2004. "A physical map of the chicken genome," Nature, Nature, vol. 432(7018), pages 761-764, December.
  • Handle: RePEc:nat:nature:v:432:y:2004:i:7018:d:10.1038_nature03030
    DOI: 10.1038/nature03030
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature03030
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature03030?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:432:y:2004:i:7018:d:10.1038_nature03030. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.