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Navigating the signalling network in mouse cardiac myocytes

Author

Listed:
  • Gilberto R. Sambrano

    (University of California, San Francisco)

  • Iain Fraser

    (147-75, California Institute of Technology)

  • Heping Han

    (University of Texas Southwestern Medical Center)

  • Yan Ni

    (University of Texas Southwestern Medical Center)

  • Tim O'Connell

    (San Francisco Veterans Administration Medical Center)

  • Zhen Yan

    (University of Texas Southwestern Medical Center
    Duke University)

  • James T. Stull

    (University of Texas Southwestern Medical Center)

Abstract

Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart. This network is an appealing model system in which to study the basic principles underlying cellular signalling mechanisms. Progress in this effort has come through the establishment of standardized myocyte isolation and culture procedures and characterization of important signalling responses.

Suggested Citation

  • Gilberto R. Sambrano & Iain Fraser & Heping Han & Yan Ni & Tim O'Connell & Zhen Yan & James T. Stull, 2002. "Navigating the signalling network in mouse cardiac myocytes," Nature, Nature, vol. 420(6916), pages 712-714, December.
    • Handle: RePEc:nat:nature:v:420:y:2002:i:6916:d:10.1038_nature01306
    DOI: 10.1038/nature01306
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