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The involvement of RNA in ribosome function

Author

Listed:
  • Peter B. Moore

    (Yale University
    Yale University)

  • Thomas A. Steitz

    (Yale University
    Yale University
    Howard Hughes Medical Institute)

Abstract

The ribosome is a particle made of RNA and protein that is found in abundance in all cells that are actively making protein. It catalyses the messenger RNA-directed synthesis of proteins. Recent structural work has demonstrated a profound involvement of the ribosome's RNA component in all aspects of its function, supporting the hypothesis that proteins were added to the ribosome late in its evolution.

Suggested Citation

  • Peter B. Moore & Thomas A. Steitz, 2002. "The involvement of RNA in ribosome function," Nature, Nature, vol. 418(6894), pages 229-235, July.
    • Handle: RePEc:nat:nature:v:418:y:2002:i:6894:d:10.1038_418229a
    DOI: 10.1038/418229a
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