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Gene silencing as an adaptive defence against viruses

Author

Listed:
  • Peter M. Waterhouse

    (CSIRO Plant Industry)

  • Ming-Bo Wang

    (CSIRO Plant Industry)

  • Tony Lough

    (CSIRO Plant Industry
    HortResearch
    Genesis Research and Development Corporation)

Abstract

Gene silencing was perceived initially as an unpredictable and inconvenient side effect of introducing transgenes into plants. It now seems that it is the consequence of accidentally triggering the plant's adaptive defence mechanism against viruses and transposable elements. This recently discovered mechanism, although mechanistically different, has a number of parallels with the immune system of mammals.

Suggested Citation

  • Peter M. Waterhouse & Ming-Bo Wang & Tony Lough, 2001. "Gene silencing as an adaptive defence against viruses," Nature, Nature, vol. 411(6839), pages 834-842, June.
    • Handle: RePEc:nat:nature:v:411:y:2001:i:6839:d:10.1038_35081168
    DOI: 10.1038/35081168
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