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BRI1 and BAK1 interact with G proteins and regulate sugar-responsive growth and development in Arabidopsis

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  • Yuancheng Peng

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    Anhui Agricultural University)

  • Liangliang Chen

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    University of Chinese Academy of Sciences)

  • Shengjun Li

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)

  • Yueying Zhang

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    University of Chinese Academy of Sciences)

  • Ran Xu

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)

  • Zupei Liu

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    University of Chinese Academy of Sciences)

  • Wuxia Liu

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    University of Chinese Academy of Sciences)

  • Jingjing Kong

    (Anhui Agricultural University)

  • Xiahe Huang

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)

  • Yingchun Wang

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)

  • Beijiu Cheng

    (Anhui Agricultural University)

  • Leiying Zheng

    (Chinese Academy of Sciences)

  • Yunhai Li

    (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
    University of Chinese Academy of Sciences)

Abstract

Sugars function as signal molecules to regulate growth, development, and gene expression in plants, yeasts, and animals. A coordination of sugar availability with phytohormone signals is crucial for plant growth and development. The molecular link between sugar availability and hormone-dependent plant growth are largely unknown. Here we report that BRI1 and BAK1 are involved in sugar-responsive growth and development. Glucose influences the physical interactions and phosphorylations of BRI1 and BAK1 in a concentration-dependent manner. BRI1 and BAK1 physically interact with G proteins that are essential for mediating sugar signaling. Biochemical data show that BRI1 can phosphorylate G protein β subunit and γ subunits, and BAK1 can phosphorylate G protein γ subunits. Genetic analyses suggest that BRI1 and BAK1 function in a common pathway with G-protein subunits to regulate sugar responses. Thus, our findings reveal an important genetic and molecular mechanism by which BR receptors associate with G proteins to regulate sugar-responsive growth and development.

Suggested Citation

  • Yuancheng Peng & Liangliang Chen & Shengjun Li & Yueying Zhang & Ran Xu & Zupei Liu & Wuxia Liu & Jingjing Kong & Xiahe Huang & Yingchun Wang & Beijiu Cheng & Leiying Zheng & Yunhai Li, 2018. "BRI1 and BAK1 interact with G proteins and regulate sugar-responsive growth and development in Arabidopsis," Nature Communications, Nature, vol. 9(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-03884-8
    DOI: 10.1038/s41467-018-03884-8
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