IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v6y2015i1d10.1038_ncomms9832.html
   My bibliography  Save this article

Subwavelength imaging through ion-beam-induced upconversion

Author

Listed:
  • Zhaohong Mi

    (Centre for Ion Beam Applications, National University of Singapore)

  • Yuhai Zhang

    (National University of Singapore)

  • Sudheer Kumar Vanga

    (Centre for Ion Beam Applications, National University of Singapore)

  • Ce-Belle Chen

    (Centre for Ion Beam Applications, National University of Singapore)

  • Hong Qi Tan

    (Centre for Ion Beam Applications, National University of Singapore)

  • Frank Watt

    (Centre for Ion Beam Applications, National University of Singapore)

  • Xiaogang Liu

    (National University of Singapore
    Institute of Materials Research and Engineering, Agency for Science, Technology and Research
    Center for Functional Materials, NUS (Suzhou) Research Institute)

  • Andrew A. Bettiol

    (Centre for Ion Beam Applications, National University of Singapore
    Yale-NUS College)

Abstract

The combination of an optical microscope and a luminescent probe plays a pivotal role in biological imaging because it allows for probing subcellular structures. However, the optical resolutions are largely constrained by Abbe’s diffraction limit, and the common dye probes often suffer from photobleaching. Here we present a new method for subwavelength imaging by combining lanthanide-doped upconversion nanocrystals with the ionoluminescence imaging technique. We experimentally observed that the ion beam can be used as a new form of excitation source to induce photon upconversion in lanthanide-doped nanocrystals. This approach enables luminescence imaging and simultaneous mapping of cellular structures with a spatial resolution of sub-30 nm.

Suggested Citation

  • Zhaohong Mi & Yuhai Zhang & Sudheer Kumar Vanga & Ce-Belle Chen & Hong Qi Tan & Frank Watt & Xiaogang Liu & Andrew A. Bettiol, 2015. "Subwavelength imaging through ion-beam-induced upconversion," Nature Communications, Nature, vol. 6(1), pages 1-6, December.
    • Handle: RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms9832
    DOI: 10.1038/ncomms9832
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms9832
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/ncomms9832?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms9832. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.