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Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Author

Listed:
  • Catherine Igartua

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA)

  • Rachel A. Myers

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA)

  • Rasika A. Mathias

    (Johns Hopkins University)

  • Maria Pino-Yanes

    (University of California San Francisco
    CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III)

  • Celeste Eng

    (University of California San Francisco)

  • Penelope E. Graves

    (Arizona Respiratory Center and BIO5 Institute, University of Arizona)

  • Albert M. Levin

    (Henry Ford Health System)

  • Blanca E. Del-Rio-Navarro

    (Hospital Infantil de Mexico Federico Gomez)

  • Daniel J. Jackson

    (University of Wisconsin School of Medicine and Public Health)

  • Oren E. Livne

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA)

  • Nicholas Rafaels

    (Johns Hopkins University)

  • Christopher K. Edlund

    (Keck School of Medicine, University of Southern California)

  • James J. Yang

    (School of Nursing, University of Michigan)

  • Scott Huntsman

    (University of California San Francisco)

  • Muhammad T. Salam

    (Keck School of Medicine, University of Southern California)

  • Isabelle Romieu

    (International Agency for Research on Cancer)

  • Raphael Mourad

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA)

  • James E. Gern

    (University of Wisconsin School of Medicine and Public Health
    University of Wisconsin School of Medicine and Public Health)

  • Robert F. Lemanske

    (University of Wisconsin School of Medicine and Public Health
    University of Wisconsin School of Medicine and Public Health)

  • Annah Wyss

    (National Institute of Environmental Health Sciences, National Institutes of Health)

  • Jane A. Hoppin

    (National Institute of Environmental Health Sciences, National Institutes of Health
    North Carolina State University)

  • Kathleen C. Barnes

    (Johns Hopkins University)

  • Esteban G. Burchard

    (University of California San Francisco
    University of California San Francisco)

  • W. James Gauderman

    (Keck School of Medicine, University of Southern California)

  • Fernando D. Martinez

    (Arizona Respiratory Center and BIO5 Institute, University of Arizona)

  • Benjamin A. Raby

    (Harvard Medical School
    Harvard Medical School)

  • Scott T. Weiss

    (Harvard Medical School)

  • L. Keoki Williams

    (Center for Health Policy and Health Services Research, Henry Ford Health System
    Henry Ford Health System)

  • Stephanie J. London

    (National Institute of Environmental Health Sciences, National Institutes of Health)

  • Frank D. Gilliland

    (Keck School of Medicine, University of Southern California)

  • Dan L. Nicolae

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
    University of Chicago)

  • Carole Ober

    (University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA)

Abstract

Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (

Suggested Citation

  • Catherine Igartua & Rachel A. Myers & Rasika A. Mathias & Maria Pino-Yanes & Celeste Eng & Penelope E. Graves & Albert M. Levin & Blanca E. Del-Rio-Navarro & Daniel J. Jackson & Oren E. Livne & Nichol, 2015. "Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma," Nature Communications, Nature, vol. 6(1), pages 1-8, May.
  • Handle: RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms6965
    DOI: 10.1038/ncomms6965
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