IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v5y2014i1d10.1038_ncomms6898.html
   My bibliography  Save this article

A strain-absorbing design for tissue–machine interfaces using a tunable adhesive gel

Author

Listed:
  • Sungwon Lee

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Yusuke Inoue

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Dongmin Kim

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Amir Reuveny

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Kazunori Kuribara

    (The University of Tokyo
    Present address: National Institute of Advanced Industrial Science and Technology, Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan)

  • Tomoyuki Yokota

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Jonathan Reeder

    (The University of Tokyo
    Present address: Department of Materials Science and Engineering, The University of Texas at Dallas, 800 W Campbell Road, Richardson, Texas 75080–3021, USA)

  • Masaki Sekino

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

  • Tsuyoshi Sekitani

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST)
    The Institute of Scientific and Industrial Research, Osaka University)

  • Yusuke Abe

    (Graduate School of Medicine, The University of Tokyo)

  • Takao Someya

    (The University of Tokyo
    Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST))

Abstract

To measure electrophysiological signals from the human body, it is essential to establish stable, gentle and nonallergic contacts between the targeted biological tissue and the electrical probes. However, it is difficult to form a stable interface between the two for long periods, especially when the surface of the biological tissue is wet and/or the tissue exhibits motion. Here we resolve this difficulty by designing and fabricating smart, stress-absorbing electronic devices that can adhere to wet and complex tissue surfaces and allow for reliable, long-term measurements of vital signals. We demonstrate a multielectrode array, which can be attached to the surface of a rat heart, resulting in good conformal contact for more than 3 h. Furthermore, we demonstrate arrays of highly sensitive, stretchable strain sensors using a similar design. Ultra-flexible electronics with enhanced adhesion to tissue could enable future applications in chronic in vivo monitoring of biological signals.

Suggested Citation

  • Sungwon Lee & Yusuke Inoue & Dongmin Kim & Amir Reuveny & Kazunori Kuribara & Tomoyuki Yokota & Jonathan Reeder & Masaki Sekino & Tsuyoshi Sekitani & Yusuke Abe & Takao Someya, 2014. "A strain-absorbing design for tissue–machine interfaces using a tunable adhesive gel," Nature Communications, Nature, vol. 5(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:5:y:2014:i:1:d:10.1038_ncomms6898
    DOI: 10.1038/ncomms6898
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms6898
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/ncomms6898?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:5:y:2014:i:1:d:10.1038_ncomms6898. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.