Author
Listed:
- Michelle Erika-Florence
(The Brain and Mind Institute, University of Western Ontario, London)
- Robert Leech
(The Cognitive, Computational and Clinical Neurosciences Lab, Imperial College London)
- Adam Hampshire
(The Brain and Mind Institute, University of Western Ontario, London
The Cognitive, Computational and Clinical Neurosciences Lab, Imperial College London)
Abstract
Inferior frontal cortex (IFC) modules that inhibit dominant behaviours are a popular feature in theories of cognitive dysfunction. However, the paradigms on which these theories are based fail to distinguish between inhibitory and non-inhibitory cognitive demands. Here we use four novel fMRI variants of the classic stop-signal task to test whether the IFC houses unique inhibitory modules. Our results demonstrate that IFC sub-regions are not functionally unique in their sensitivities to inhibitory cognitive demands, but instead form components of spatially distributed networks. These networks are most strongly activated when infrequent stimuli are being processed, regardless of behavioural inhibitory demands, and when novel tasks are being acquired, as opposed to when routine responses must be suppressed. We propose that there are no inhibitory modules within the frontal lobes and that behavioural inhibition is an emergent property of spatially distributed functional networks, each of which supports a broader class of cognitive demands.
Suggested Citation
Michelle Erika-Florence & Robert Leech & Adam Hampshire, 2014.
"A functional network perspective on response inhibition and attentional control,"
Nature Communications, Nature, vol. 5(1), pages 1-12, September.
Handle:
RePEc:nat:natcom:v:5:y:2014:i:1:d:10.1038_ncomms5073
DOI: 10.1038/ncomms5073
Download full text from publisher
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:5:y:2014:i:1:d:10.1038_ncomms5073. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
We have no bibliographic references for this item. You can help adding them by using this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through
the various RePEc services.