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Carbon nanotube–liposome supramolecular nanotrains for intelligent molecular-transport systems

Author

Listed:
  • Eijiro Miyako

    (Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST))

  • Kenji Kono

    (Osaka Prefecture University)

  • Eiji Yuba

    (Osaka Prefecture University)

  • Chie Hosokawa

    (Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST))

  • Hidenori Nagai

    (Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST))

  • Yoshihisa Hagihara

    (Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST))

Abstract

Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.

Suggested Citation

  • Eijiro Miyako & Kenji Kono & Eiji Yuba & Chie Hosokawa & Hidenori Nagai & Yoshihisa Hagihara, 2012. "Carbon nanotube–liposome supramolecular nanotrains for intelligent molecular-transport systems," Nature Communications, Nature, vol. 3(1), pages 1-9, January.
    • Handle: RePEc:nat:natcom:v:3:y:2012:i:1:d:10.1038_ncomms2233
    DOI: 10.1038/ncomms2233
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