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Photon diffusion near the point-of-entry in anisotropically scattering turbid media

Author

Listed:
  • Edward Vitkin

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

  • Vladimir Turzhitsky

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

  • Le Qiu

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

  • Lianyu Guo

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

  • Irving Itzkan

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

  • Eugene B. Hanlon

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center
    Medical Research Service and Geriatric Research Education and Clinical Center)

  • Lev T. Perelman

    (Center for Advanced Biomedical Imaging and Photonics, Harvard University and Beth Israel Deaconess Medical Center)

Abstract

From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. However, light propagation near the point-of-entry in turbid media has never been analytically described, until now. Here we report a straightforward and accurate method that overcomes this longstanding, unsolved problem in radiative transport. Our theory properly treats anisotropic photon scattering events and takes the specific form of the phase function into account. As a result, our method correctly predicts the spatially dependent diffuse reflectance of light near the point-of-entry for any arbitrary phase function. We demonstrate that the theory is in excellent agreement with both experimental results and Monte Carlo simulations for several commonly used phase functions.

Suggested Citation

  • Edward Vitkin & Vladimir Turzhitsky & Le Qiu & Lianyu Guo & Irving Itzkan & Eugene B. Hanlon & Lev T. Perelman, 2011. "Photon diffusion near the point-of-entry in anisotropically scattering turbid media," Nature Communications, Nature, vol. 2(1), pages 1-8, September.
    • Handle: RePEc:nat:natcom:v:2:y:2011:i:1:d:10.1038_ncomms1599
    DOI: 10.1038/ncomms1599
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