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Dynamic rigidity changes enable rapid cell migration on soft substrates

Author

Listed:
  • Jiapeng Yang

    (Jinan Microecological Biomedicine Shandong Laboratory
    Nanjing University
    Sichuan University)

  • Yu Zhang

    (Jinan Microecological Biomedicine Shandong Laboratory
    Nanjing University)

  • Shuo Wang

    (Nanjing University)

  • Peng Wang

    (Sichuan University)

  • Liang Dong

    (Nanjing University)

  • Luofei Li

    (Nanjing University)

  • Yuanqi Cheng

    (Nanjing University)

  • Xiaoyu Huang

    (Nanjing University)

  • Bin Xue

    (Nanjing University)

  • Wei Wang

    (Nanjing University)

  • Chunping Jiang

    (Jinan Microecological Biomedicine Shandong Laboratory
    Nanjing University)

  • Xiaosong Gu

    (Jinan Microecological Biomedicine Shandong Laboratory
    Nanjing University
    Nantong University)

  • Yi Cao

    (Jinan Microecological Biomedicine Shandong Laboratory
    Nanjing University
    University of Chinese Academy of Sciences
    Nanjing University)

  • Qiang Wei

    (Sichuan University)

Abstract

Cell migration is crucial in various biological processes, regulated by surrounding rigidity. Studies under static conditions suggest migration favors rigid substrates, as softer substrates (

Suggested Citation

  • Jiapeng Yang & Yu Zhang & Shuo Wang & Peng Wang & Liang Dong & Luofei Li & Yuanqi Cheng & Xiaoyu Huang & Bin Xue & Wei Wang & Chunping Jiang & Xiaosong Gu & Yi Cao & Qiang Wei, 2025. "Dynamic rigidity changes enable rapid cell migration on soft substrates," Nature Communications, Nature, vol. 16(1), pages 1-17, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-63854-9
    DOI: 10.1038/s41467-025-63854-9
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