Author
Listed:
- Francesca Dell’Eva
(Politecnico di Milano
Politecnico di Milano, Polo Territoriale di Lecco)
- Eleonora Guanziroli
(Villa Beretta Rehabilitation Center)
- Viola Camerini
(Politecnico di Milano
Politecnico di Milano, Polo Territoriale di Lecco)
- Marta Gandolla
(Politecnico di Milano, Polo Territoriale di Lecco
Politecnico di Milano)
- Laura Brignole
(Politecnico di Milano
Politecnico di Milano, Polo Territoriale di Lecco)
- Stefano Maludrottu
(Italian Institute of Technology IIT)
- Emanuele Gruppioni
(Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro)
- Giancarlo Ferrigno
(Politecnico di Milano)
- Franco Molteni
(Villa Beretta Rehabilitation Center)
- Emilia Ambrosini
(Politecnico di Milano
Politecnico di Milano, Polo Territoriale di Lecco)
- Alessandra Pedrocchi
(Politecnico di Milano
Politecnico di Milano, Polo Territoriale di Lecco)
Abstract
The integration of robotics and Electrical Stimulation (ES) in neurorehabilitation leverages robotics’ precise task execution alongside ES-induced motor learning, muscle conditioning, and cardiovascular benefits. We propose a hybrid system for overground gait training, combining neuromuscular ES and a motorized exoskeleton. Different combination modalities are proposed: ES-motor cooperation for the swinging knee, synchronized but independent ES and motor assistance for hip movements and for the knee during stance, and ES-only for the non-actuated ankle. Twelve non-disabled subjects and eleven participants with neurological disorders tested the system under two conditions: exoskeleton-only and hybrid. The hybrid condition reduced knee motor torque by 48% during swing without compromising tracking accuracy, showing that ES can effectively drive limb motion. Neurological participants rated the hybrid system as more usable than the exoskeleton alone (median 5-point improvement of System Usability Scale). These findings support the feasibility of hybrid ES-motorized exoskeletons in clinical settings. Future studies should investigate their potential to enhance therapeutic outcomes.
Suggested Citation
Francesca Dell’Eva & Eleonora Guanziroli & Viola Camerini & Marta Gandolla & Laura Brignole & Stefano Maludrottu & Emanuele Gruppioni & Giancarlo Ferrigno & Franco Molteni & Emilia Ambrosini & Alessan, 2025.
"A multifaceted hybrid ES-robotic device for gait training in individuals with neurological disorders,"
Nature Communications, Nature, vol. 16(1), pages 1-16, December.
Handle:
RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-63474-3
DOI: 10.1038/s41467-025-63474-3
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