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Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy

Author

Listed:
  • Tesen Zhang

    (University of Macau
    Fuzhou University)

  • Quansheng Cheng

    (University of Macau)

  • Hongwei Cheng

    (University of Macau)

  • Qingcheng Wang

    (University of Macau)

  • Bingzhe Wang

    (University of Macau)

  • Bohan Zhang

    (University of Macau)

  • Handong Sun

    (University of Macau)

  • Chuxia Deng

    (University of Macau
    University of Macau)

  • Zikang Tang

    (University of Macau
    University of Macau)

Abstract

The magnetic quantum phenomena triggered by electrons in carbon-based materials are challenging to decipher and exploit, thus sparking extensive research interest. Carbon quantum dots (CQDs), emerging candidates in nanomedicine, exhibit fascinating behaviors related to electron spin, relaxation, and migration. Herein, we report a magnetic edge state structure within nonmetallic CQDs that generates nitrogen hyperfine splitting at room temperature. Furthermore, a series of near-infrared (NIR) absorption bandgaps are produced based on spin–orbit coupling and dipole–dipole interactions, exhibiting potential in photothermal and thermoelectric catalysis. By modulating the surface ligands and solvent, relaxation rates are accelerated through spin averaging, which results in CQDs serving as desirable T1 contrast agents with the highest relaxivity for magnetic resonance imaging (MRI) and NIR-II cancer therapy agents. Combining these characteristics, we propose an MRI-guided approach to precision cancer therapy that offers a pathway for the rapid advancement of nanomedicine.

Suggested Citation

  • Tesen Zhang & Quansheng Cheng & Hongwei Cheng & Qingcheng Wang & Bingzhe Wang & Bohan Zhang & Handong Sun & Chuxia Deng & Zikang Tang, 2025. "Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy," Nature Communications, Nature, vol. 16(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-60951-7
    DOI: 10.1038/s41467-025-60951-7
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    1. Bruno de la Torre & Martin Švec & Prokop Hapala & Jesus Redondo & Ondřej Krejčí & Rabindranath Lo & Debashree Manna & Amrit Sarmah & Dana Nachtigallová & Jiří Tuček & Piotr Błoński & Michal Otyepka & , 2018. "Non-covalent control of spin-state in metal-organic complex by positioning on N-doped graphene," Nature Communications, Nature, vol. 9(1), pages 1-9, December.
    2. Michael Slota & Ashok Keerthi & William K. Myers & Evgeny Tretyakov & Martin Baumgarten & Arzhang Ardavan & Hatef Sadeghi & Colin J. Lambert & Akimitsu Narita & Klaus Müllen & Lapo Bogani, 2018. "Publisher Correction: Magnetic edge states and coherent manipulation of graphene nanoribbons," Nature, Nature, vol. 561(7723), pages 31-31, September.
    3. Annika Kurzmann & Yaakov Kleeorin & Chuyao Tong & Rebekka Garreis & Angelika Knothe & Marius Eich & Christopher Mittag & Carolin Gold & Folkert Kornelis Vries & Kenji Watanabe & Takashi Taniguchi & Vl, 2021. "Kondo effect and spin–orbit coupling in graphene quantum dots," Nature Communications, Nature, vol. 12(1), pages 1-6, December.
    4. L. Banszerus & S. Möller & C. Steiner & E. Icking & S. Trellenkamp & F. Lentz & K. Watanabe & T. Taniguchi & C. Volk & C. Stampfer, 2021. "Spin-valley coupling in single-electron bilayer graphene quantum dots," Nature Communications, Nature, vol. 12(1), pages 1-7, December.
    5. L. Banszerus & S. Möller & K. Hecker & E. Icking & K. Watanabe & T. Taniguchi & F. Hassler & C. Volk & C. Stampfer, 2023. "Particle–hole symmetry protects spin-valley blockade in graphene quantum dots," Nature, Nature, vol. 618(7963), pages 51-56, June.
    6. Manabendra Kuiri & Christopher Coleman & Zhenxiang Gao & Aswin Vishnuradhan & Kenji Watanabe & Takashi Taniguchi & Jihang Zhu & Allan H. MacDonald & Joshua Folk, 2022. "Spontaneous time-reversal symmetry breaking in twisted double bilayer graphene," Nature Communications, Nature, vol. 13(1), pages 1-6, December.
    7. Bijiang Geng & Jinyan Hu & Yuan Li & Shini Feng & Dengyu Pan & Lingyan Feng & Longxiang Shen, 2022. "Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    8. Michael Slota & Ashok Keerthi & William K. Myers & Evgeny Tretyakov & Martin Baumgarten & Arzhang Ardavan & Hatef Sadeghi & Colin J. Lambert & Akimitsu Narita & Klaus Müllen & Lapo Bogani, 2018. "Magnetic edge states and coherent manipulation of graphene nanoribbons," Nature, Nature, vol. 557(7707), pages 691-695, May.
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