The NELF pausing checkpoint mediates the functional divergence of Cdk9
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DOI: 10.1038/s41467-023-38359-y
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- Saskia Gressel & Björn Schwalb & Patrick Cramer, 2019. "The pause-initiation limit restricts transcription activation in human cells," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
- Gregory T. Booth & Pabitra K. Parua & Miriam Sansó & Robert P. Fisher & John T. Lis, 2018. "Cdk9 regulates a promoter-proximal checkpoint to modulate RNA polymerase II elongation rate in fission yeast," Nature Communications, Nature, vol. 9(1), pages 1-10, December.
- Seychelle M. Vos & Lucas Farnung & Henning Urlaub & Patrick Cramer, 2018. "Structure of paused transcription complex Pol II–DSIF–NELF," Nature, Nature, vol. 560(7720), pages 601-606, August.
- Seychelle M. Vos & Lucas Farnung & Marc Boehning & Christoph Wigge & Andreas Linden & Henning Urlaub & Patrick Cramer, 2018. "Structure of activated transcription complex Pol II–DSIF–PAF–SPT6," Nature, Nature, vol. 560(7720), pages 607-612, August.
- Anthony C. Bishop & Jeffrey A. Ubersax & Dejah T. Petsch & Dina P. Matheos & Nathanael S. Gray & Justin Blethrow & Eiji Shimizu & Joe Z. Tsien & Peter G. Schultz & Mark D. Rose & John L. Wood & David , 2000. "A chemical switch for inhibitor-sensitive alleles of any protein kinase," Nature, Nature, vol. 407(6802), pages 395-401, September.
- Jie Yao & Katherine M. Munson & Watt W. Webb & John T. Lis, 2006. "Dynamics of heat shock factor association with native gene loci in living cells," Nature, Nature, vol. 442(7106), pages 1050-1053, August.
- Patrick Cramer, 2019. "Organization and regulation of gene transcription," Nature, Nature, vol. 573(7772), pages 45-54, September.
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- Krzysztof Kuś & Loic Carrique & Tea Kecman & Marjorie Fournier & Sarah Sayed Hassanein & Ebru Aydin & Cornelia Kilchert & Jonathan M. Grimes & Lidia Vasiljeva, 2025. "DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
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