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Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States

Author

Listed:
  • Bingyi Yang

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Angkana T. Huang

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Bernardo Garcia-Carreras

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • William E. Hart

    (Sandia National Laboratories)

  • Andrea Staid

    (Sandia National Laboratories)

  • Matt D. T. Hitchings

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Elizabeth C. Lee

    (Johns Hopkins Bloomberg School of Public Health)

  • Chanelle J. Howe

    (Brown University School of Public Health)

  • Kyra H. Grantz

    (Johns Hopkins Bloomberg School of Public Health)

  • Amy Wesolowksi

    (Johns Hopkins Bloomberg School of Public Health)

  • Joseph Chadi Lemaitre

    (École Polytechnique Fédérale de Lausanne)

  • Susan Rattigan

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Carlos Moreno

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Brooke A. Borgert

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

  • Celeste Dale

    (University of Florida)

  • Nicole Quigley

    (University of Florida)

  • Andrew Cummings

    (Syracuse University)

  • Alizée McLorg

    (Syracuse University)

  • Kaelene LoMonaco

    (University of Florida)

  • Sarah Schlossberg

    (Tulane University)

  • Drew Barron-Kraus

    (University of Florida)

  • Harrison Shrock

    (University of Florida)

  • Justin Lessler

    (Johns Hopkins Bloomberg School of Public Health)

  • Carl D. Laird

    (Sandia National Laboratories)

  • Derek A. T. Cummings

    (University of Florida
    Emerging Pathogens Institute, University of Florida)

Abstract

Non-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (Reff) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median Reff below 1 when combined with either stay at home orders (median Reff 0.97, 95% confidence interval (CI) 0.58–1.39) or face masks (median Reff 0.97, 95% CI 0.58–1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.

Suggested Citation

  • Bingyi Yang & Angkana T. Huang & Bernardo Garcia-Carreras & William E. Hart & Andrea Staid & Matt D. T. Hitchings & Elizabeth C. Lee & Chanelle J. Howe & Kyra H. Grantz & Amy Wesolowksi & Joseph Chadi, 2021. "Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
  • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-23865-8
    DOI: 10.1038/s41467-021-23865-8
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    Cited by:

    1. Virat Agrawal & Jonathan H. Cantor & Neeraj Sood & Christopher M. Whaley, 2021. "The Impact of the COVID-19 Vaccine Distribution on Mental Health Outcomes," NBER Working Papers 29593, National Bureau of Economic Research, Inc.

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