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Photodegradation of carbon dots cause cytotoxicity

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  • Yue-Yue Liu

    (Nanjing University)

  • Nan-Yang Yu

    (Nanjing University)

  • Wen-Di Fang

    (Nanjing University)

  • Qiao-Guo Tan

    (Xiamen University)

  • Rong Ji

    (Nanjing University)

  • Liu-Yan Yang

    (Nanjing University)

  • Si Wei

    (Nanjing University)

  • Xiao-Wei Zhang

    (Nanjing University)

  • Ai-Jun Miao

    (Nanjing University)

Abstract

Carbon dots (CDs) are photoluminescent nanomaterials with wide-ranging applications. Despite their photoactivity, it remains unknown whether CDs degrade under illumination and whether such photodegradation poses any cytotoxic effects. Here, we show laboratory-synthesized CDs irradiated with light degrade into molecules that are toxic to both normal (HEK-293) and cancerous (HeLa and HepG2) human cells. Eight days of irradiation photolyzes 28.6-59.8% of the CDs to

Suggested Citation

  • Yue-Yue Liu & Nan-Yang Yu & Wen-Di Fang & Qiao-Guo Tan & Rong Ji & Liu-Yan Yang & Si Wei & Xiao-Wei Zhang & Ai-Jun Miao, 2021. "Photodegradation of carbon dots cause cytotoxicity," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-21080-z
    DOI: 10.1038/s41467-021-21080-z
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