IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v11y2020i1d10.1038_s41467-020-17456-2.html
   My bibliography  Save this article

Decreased bioefficacy of long-lasting insecticidal nets and the resurgence of malaria in Papua New Guinea

Author

Listed:
  • Rebecca Vinit

    (PNG Institute of Medical Research)

  • Lincoln Timinao

    (PNG Institute of Medical Research
    James Cook University)

  • Nakei Bubun

    (PNG Institute of Medical Research)

  • Michelle Katusele

    (PNG Institute of Medical Research)

  • Leanne J. Robinson

    (PNG Institute of Medical Research
    Burnet Institute)

  • Peter Kaman

    (PNG Institute of Medical Research)

  • Muker Sakur

    (PNG Institute of Medical Research)

  • Leo Makita

    (National Department of Health)

  • Lisa Reimer

    (Liverpool School of Tropical Medicine)

  • Louis Schofield

    (James Cook University)

  • William Pomat

    (PNG Institute of Medical Research)

  • Ivo Mueller

    (Walter and Eliza Hall Institute of Medical Research, 1G)

  • Moses Laman

    (PNG Institute of Medical Research)

  • Tim Freeman

    (Rotarians Against Malaria)

  • Stephan Karl

    (PNG Institute of Medical Research
    James Cook University)

Abstract

Papua New Guinea (PNG) has the highest malaria transmission outside of Africa. Long-lasting insecticidal nets (LLINs) are believed to have helped to reduce average malaria prevalence in PNG from 16% in 2008 to 1% in 2014. Since 2015 malaria in PNG has resurged significantly. Here, we present observations documenting decreased bioefficacy of unused LLINs with manufacturing dates between 2013 and 2019 collected from villages and LLIN distributors in PNG. Specifically, we show that of n = 167 tested LLINs manufactured after 2013, only 17% are fulfilling the required World Health Organisation bioefficacy standards of ≥ 80% 24 h mortality or ≥ 95% 60 min knockdown in bioassays with pyrethroid susceptible Anopheles farauti mosquitoes. In contrast, all (100%, n = 25) LLINs with manufacturing dates prior to 2013 are meeting these bioefficacy standards. These results suggest that decreased bioefficacy of LLINs is contributing to the malaria resurgence in PNG and increased scrutiny of LLIN quality is warranted.

Suggested Citation

  • Rebecca Vinit & Lincoln Timinao & Nakei Bubun & Michelle Katusele & Leanne J. Robinson & Peter Kaman & Muker Sakur & Leo Makita & Lisa Reimer & Louis Schofield & William Pomat & Ivo Mueller & Moses La, 2020. "Decreased bioefficacy of long-lasting insecticidal nets and the resurgence of malaria in Papua New Guinea," Nature Communications, Nature, vol. 11(1), pages 1-7, December.
    • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-17456-2
    DOI: 10.1038/s41467-020-17456-2
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-020-17456-2
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-020-17456-2?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-17456-2. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.