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A Semidefinite Programming-Based Branch-and-Cut Algorithm for Biclustering

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  • Antonio M. Sudoso

    (Department of Computer, Control and Management Engineering “Antonio Ruberti,” Sapienza University of Rome, 00185 Rome, Italy)

Abstract

Biclustering, also called co-clustering, block clustering, or two-way clustering, involves the simultaneous clustering of both the rows and the columns of a data matrix into distinct groups such that the rows and columns within a group display similar patterns. As a model problem for biclustering, we consider the k -densest disjoint biclique problem, whose goal is to identify k disjoint complete bipartite subgraphs (called bicliques) of a given weighted complete bipartite graph such that the sum of their densities is maximized. To address this problem, we present a tailored branch-and-cut algorithm. For the upper-bound routine, we consider a semidefinite programming relaxation and propose valid inequalities to strengthen the bound. We solve this relaxation in a cutting-plane fashion using a first-order method. For the lower bound, we design a maximum weight matching rounding procedure that exploits the solution of the relaxation solved at each node. Computational results on both synthetic and real-world instances show that the proposed algorithm can solve instances approximately 20 times larger than those handled by general-purpose solvers.

Suggested Citation

  • Antonio M. Sudoso, 2025. "A Semidefinite Programming-Based Branch-and-Cut Algorithm for Biclustering," INFORMS Journal on Computing, INFORMS, vol. 37(6), pages 1433-1456, November.
  • Handle: RePEc:inm:orijoc:v:37:y:2025:i:6:p:1433-1456
    DOI: 10.1287/ijoc.2024.0683
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