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Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3

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  • Sivashankari Selvarajan
  • Piramanayagam Shanmughavel

Abstract

In biochemistry, a hypothetical protein encoded by a hypothetical gene is a protein whose existence has been predicted, for which there is no experimental evidence for expression in vivo. As a result, the function of such genes is not known. Despite several efforts, only 50-60 % of genes have been annotated in most completely sequenced genomes and their functions are known. The rest 40% of the genes in any genome is totally unknown in terms of its functions. As of September 2010, there are around 637 genes encoded as Hypothetical in NCBI. So, the present investigation focused on functional annotation of hypothetical genes in the Chromosome 3 of the Human Genome.

Suggested Citation

  • Sivashankari Selvarajan & Piramanayagam Shanmughavel, 2016. "Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3," International Journal of Scientific Research in Science, Engineering and Technology, International Journal of Scientific Research in Science, Engineering and Technology, vol. 2(2), pages 337-343, December.
    • Handle: RePEc:ijs:ijsrse:v2:y2016:i2:id:hijsrset1622104
    Note: Article URL: https://ijsrset.com/IJSRSET1622104
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