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Robust Genetic Circuit Design: A Mixed and IQC Analysis

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  • Ruijuan Chen
  • Wei Pan
  • Dongfei Fu
  • Xin He

Abstract

This paper considers the problem of designing a genetic circuit which is robust to noise effect. To achieve this goal, a mixed and Integral Quadratic Constraints (IQC) approach is proposed. In order to minimize the effects of external noise on the genetic regulatory network in terms of norm, a design procedure of Hill coefficients in the promoters is presented. The IQC approach is introduced to analyze and guarantee the stability of the designed circuit.

Suggested Citation

  • Ruijuan Chen & Wei Pan & Dongfei Fu & Xin He, 2017. "Robust Genetic Circuit Design: A Mixed and IQC Analysis," Advances in Mathematical Physics, Hindawi, vol. 2017, pages 1-6, April.
    • Handle: RePEc:hin:jnlamp:5757943
    DOI: 10.1155/2017/5757943
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