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Hopf Bifurcation of a Mathematical Model for Growth of Tumors with an Action of Inhibitor and Two Time Delays

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  • Bao Shi
  • Fangwei Zhang
  • Shihe Xu

Abstract

A mathematical model for growth of tumors with two discrete delays is studied. The delays, respectively, represent the time taken for cells to undergo mitosis and the time taken for the cell to modify the rate of cell loss due to apoptosis and kill of cells by the inhibitor. We show the influence of time delays on the Hopf bifurcation when one of delays is used as a bifurcation parameter.

Suggested Citation

  • Bao Shi & Fangwei Zhang & Shihe Xu, 2011. "Hopf Bifurcation of a Mathematical Model for Growth of Tumors with an Action of Inhibitor and Two Time Delays," Abstract and Applied Analysis, Hindawi, vol. 2011, pages 1-10, March.
  • Handle: RePEc:hin:jnlaaa:980686
    DOI: 10.1155/2011/980686
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    Cited by:

    1. Zhou, Haihua & Wang, Zejia & Yuan, Daming & Song, Huijuan, 2021. "Hopf bifurcation of a free boundary problem modeling tumor growth with angiogenesis and two time delays," Chaos, Solitons & Fractals, Elsevier, vol. 153(P1).

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