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A Mathematical Model on the Dynamics of In-Host Infection Cholera Disease with Vaccination

Author

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  • Owade Kennedy Jackob
  • Okaka Akinyi
  • Frankline Tireito
  • Filippo Cacace

Abstract

In this paper, a within-host cholera mathematical model has been developed using a system of ordinary differential equations incorporating vaccine efficacy. The formulated model considers cells in an already vaccinated individual with a vaccine whose efficacy is γ. The solutions of the model have been shown to be both positive and bounded hence well-posed. The vaccine basic reproduction number has been carried out using the next generation matrix approach and is given by R0V=γ/d+μ2 and R0V 1. Furthermore, analysis of the model shows that R0V

Suggested Citation

  • Owade Kennedy Jackob & Okaka Akinyi & Frankline Tireito & Filippo Cacace, 2023. "A Mathematical Model on the Dynamics of In-Host Infection Cholera Disease with Vaccination," Discrete Dynamics in Nature and Society, Hindawi, vol. 2023, pages 1-11, March.
    • Handle: RePEc:hin:jnddns:1465228
    DOI: 10.1155/2023/1465228
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