A Systematic Review on the Intersection of the Cold Chain and Digital Transformation

Digital transformation (DT) is reshaping cold chain operations through technologies such as the Internet of Things (IoT), artificial intelligence (AI), blockchain, and digital twins. However, evidence remains fragmented, and a systematic synthesis focused on how these technologies affect cold chain performance, sustainability, and cost-efficiency is limited. This PRISMA-based systematic literature review analyzes 107 studies published between 2009 and 2025 to examine enabling technologies and application areas, operational and sustainability impacts, and the main adoption challenges. The reviewed evidence suggests that digitalization can improve real-time visibility, temperature control, traceability, and energy management, supporting waste reduction and improved quality assurance. Key challenges include high implementation costs and uncertain returns on investment, interoperability constraints, data governance and cybersecurity concerns, and organizational readiness gaps. The paper concludes with implications for managers and policymakers and a future research agenda emphasizing integrated multi-technology solutions, standardized sustainability assessment, and rigorous validation through pilots, testbeds, and real-world deployments to enable scalable and resilient cold chain digitalization.