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Hybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease

Author

Listed:
  • Chitradevi Dhakhinamoorthy

    (Department of Computer Science and Engineering, Hindustan Institute of Technology and Science, Chennai 600016, India)

  • Sathish Kumar Mani

    (Department of Computer Applications, Hindustan Institute of Technology and Science, Chennai 600016, India)

  • Sandeep Kumar Mathivanan

    (School of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, India)

  • Senthilkumar Mohan

    (School of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, India)

  • Prabhu Jayagopal

    (School of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, India)

  • Saurav Mallik

    (Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA
    Department of Pharmacology & Toxicology, The University of Arizona, Tucson, AZ 85721, USA)

  • Hong Qin

    (Department of Computer Science and Engineering, University of Tennessee at Chattanooga, Chattanooga, TN 37403, USA)

Abstract

In recent years, finding the optimal solution for image segmentation has become more important in many applications. The whale optimization algorithm (WOA) is a metaheuristic optimization technique that has the advantage of achieving the global optimal solution while also being simple to implement and solving many real-time problems. If the complexity of the problem increases, the WOA may stick to local optima rather than global optima. This could be an issue in obtaining a better optimal solution. For this reason, this paper recommends a hybrid algorithm that is based on a mixture of the WOA and gray wolf optimization (GWO) for segmenting the brain sub regions, such as the gray matter (GM), white matter (WM), ventricle, corpus callosum (CC), and hippocampus (HC). This hybrid mixture consists of two steps, i.e., the WOA and GWO. The proposed method helps in diagnosing Alzheimer’s disease (AD) by segmenting the brain sub regions (SRs) by using a hybrid of the WOA and GWO (H-WOA-GWO, which is represented as HWGO). The segmented region was validated with different measures, and it shows better accuracy results of 92%. Following segmentation, the deep learning classifier was utilized to categorize normal and AD images. The combination of WOA and GWO yields an accuracy of 90%. As a result, it was discovered that the suggested method is a highly successful technique for identifying the ideal solution, and it is paired with a deep learning algorithm for classification.

Suggested Citation

  • Chitradevi Dhakhinamoorthy & Sathish Kumar Mani & Sandeep Kumar Mathivanan & Senthilkumar Mohan & Prabhu Jayagopal & Saurav Mallik & Hong Qin, 2023. "Hybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease," Mathematics, MDPI, vol. 11(5), pages 1-17, February.
  • Handle: RePEc:gam:jmathe:v:11:y:2023:i:5:p:1136-:d:1079544
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    References listed on IDEAS

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    1. Nisha Puthiyedth & Carlos Riveros & Regina Berretta & Pablo Moscato, 2016. "Identification of Differentially Expressed Genes through Integrated Study of Alzheimer’s Disease Affected Brain Regions," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-29, April.
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