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Perioperative Management of Antithrombotic Therapy in Patients Who Undergo Dental Procedures: A Systematic Review of the Literature and Network Meta-Analysis

Author

Listed:
  • Andrea Boccatonda

    (Internal Medicine, Bentivoglio Hospital, AUSL Bologna, 40010 Bentivoglio, Italy
    These authors contributed equally to this work.)

  • Alessio Frisone

    (Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100 Chieti, Italy
    These authors contributed equally to this work.)

  • Felice Lorusso

    (Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100 Chieti, Italy
    These authors contributed equally to this work.)

  • Calogero Bugea

    (Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100 Chieti, Italy)

  • Maristella Di Carmine

    (Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100 Chieti, Italy)

  • Cosima Schiavone

    (Department of Medicine and Science of Aging, “G. d’Annunzio” University, 66100 Chieti, Italy)

  • Giulio Cocco

    (Department of Medicine and Science of Aging, “G. d’Annunzio” University, 66100 Chieti, Italy)

  • Damiano D’Ardes

    (Department of Medicine and Science of Aging, “G. d’Annunzio” University, 66100 Chieti, Italy)

  • Antonio Scarano

    (Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100 Chieti, Italy
    Department of Oral Implantology, Dental Research Division, College Ingà, UNINGÁ, Cachoeiro de Itapemirim 29312, ES, Brazil)

  • Maria Teresa Guagnano

    (Department of Medicine and Science of Aging, “G. d’Annunzio” University, 66100 Chieti, Italy)

Abstract

Background: The surgical dental treatment of subjects admitted for anticoagulants therapy represents a consistent risk for peri-operative bleeding. The aim of the present study was to investigate the clinical findings of dental surgery operative management of the patients under anticoagulants drugs protocol. Methods: The literature screening was performed using Pubmed/Medline, EMBASE and Cochrane library, considering only randomized clinical trials (RCTs) papers. No limitations about the publication’s period, follow-up time or clinical parameters were considered. Results: A total of eight RCTs were included for the qualitative synthesis. No thromboembolic complications were reported in any studies. Several bleeding episodes associated with anticoagulant drugs in dental surgery were mild and generally happened on the first day after the treatment. Conclusions: The use of local haemostatic measures is generally effective for bleeding control with no further pharmacological drug management or suspension.

Suggested Citation

  • Andrea Boccatonda & Alessio Frisone & Felice Lorusso & Calogero Bugea & Maristella Di Carmine & Cosima Schiavone & Giulio Cocco & Damiano D’Ardes & Antonio Scarano & Maria Teresa Guagnano, 2023. "Perioperative Management of Antithrombotic Therapy in Patients Who Undergo Dental Procedures: A Systematic Review of the Literature and Network Meta-Analysis," IJERPH, MDPI, vol. 20(7), pages 1-13, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:7:p:5293-:d:1109521
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    References listed on IDEAS

    as
    1. Guido Galletti & Fortunato Alfonsi & Angelo Raffaele & Nicola Alberto Valente & Sibylle Chatelain & Roni Kolerman & Chiara Cinquini & Stefano Romeggio & Giovanna Iezzi & Antonio Barone, 2020. "Implant Placement in Patients under Treatment with Rivaroxaban: A Retrospective Clinical Study," IJERPH, MDPI, vol. 17(12), pages 1-13, June.
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