IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i2p1282-d1031525.html
   My bibliography  Save this article

The Bidirectional Relationship between Pulmonary Tuberculosis and Lung Cancer

Author

Listed:
  • Mădălina Preda

    (Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania
    Microbiology, Parasitology and Virology Discipline, Department of Fundamental Sciences, Faculty of Midwives and Nursing, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
    These authors contributed equally to this work.)

  • Bogdan Cosmin Tănase

    (Department of Thoracic Surgery, Institute of Oncology “Prof. Dr. Al. Trestioreanu” Bucharest, 022328 Bucharest, Romania
    These authors contributed equally to this work.)

  • Daniela Luminița Zob

    (Department of Medical Oncology II, Institute of Oncology “Prof. Dr. Al. Trestioreanu” Bucharest, 022328 Bucharest, Romania
    These authors contributed equally to this work.)

  • Adelina Silvana Gheorghe

    (Department of Oncology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
    Department of Medical Oncology I, Institute of Oncology “Prof. Dr. Al. Trestioreanu” Bucharest, 022328 Bucharest, Romania
    These authors contributed equally to this work.)

  • Cristian Virgil Lungulescu

    (Department of Oncology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania)

  • Elena Adriana Dumitrescu

    (Department of Oncology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania)

  • Dana Lucia Stănculeanu

    (Department of Oncology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
    Department of Medical Oncology I, Institute of Oncology “Prof. Dr. Al. Trestioreanu” Bucharest, 022328 Bucharest, Romania)

  • Loredana Sabina Cornelia Manolescu

    (Microbiology, Parasitology and Virology Discipline, Department of Fundamental Sciences, Faculty of Midwives and Nursing, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
    Department of Virology, Institute of Virology “Stefan S. Nicolau”, 030304 Bucharest, Romania)

  • Oana Popescu

    (Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania)

  • Elmira Ibraim

    (Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania)

  • Beatrice Mahler

    (Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania
    Pneumo-Phthisiology II Discipline, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania)

Abstract

Lung cancer and pulmonary tuberculosis are two significant public health problems that continue to take millions of lives each year. They may have similar symptoms and, in some cases, are diagnosed simultaneously or may have a causal relationship. In tuberculosis disease, the chronic inflammation, different produced molecules, genomic changes, and fibrosis are believed to be important factors that may promote carcinogenesis. As a reverse reaction, the development of carcinogenesis and the treatment may induce the reactivation of latent tuberculosis infection. Moreover, the recently used checkpoint inhibitors are a debatable subject since they help treat lung cancer but may lead to the reactivation of pulmonary tuberculosis and checkpoint-induced pneumonitis. Pulmonary rehabilitation is an effective intervention in post-tuberculosis patients and lung cancer patients and should be recommended to improve outcomes in these pathologies.

Suggested Citation

  • Mădălina Preda & Bogdan Cosmin Tănase & Daniela Luminița Zob & Adelina Silvana Gheorghe & Cristian Virgil Lungulescu & Elena Adriana Dumitrescu & Dana Lucia Stănculeanu & Loredana Sabina Cornelia Mano, 2023. "The Bidirectional Relationship between Pulmonary Tuberculosis and Lung Cancer," IJERPH, MDPI, vol. 20(2), pages 1-13, January.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1282-:d:1031525
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/2/1282/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/2/1282/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jing Wang & Pupu Ge & Lihua Qiang & Feng Tian & Dongdong Zhao & Qiyao Chai & Mingzhao Zhu & Rongbin Zhou & Guangxun Meng & Yoichiro Iwakura & George Fu Gao & Cui Hua Liu, 2017. "The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation," Nature Communications, Nature, vol. 8(1), pages 1-16, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Lihua Qiang & Yong Zhang & Zehui Lei & Zhe Lu & Shasha Tan & Pupu Ge & Qiyao Chai & Mengyuan Zhao & Xinwen Zhang & Bingxi Li & Yu Pang & Lingqiang Zhang & Cui Hua Liu & Jing Wang, 2023. "A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination," Nature Communications, Nature, vol. 14(1), pages 1-15, December.

    More about this item

    Keywords

    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1282-:d:1031525. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.