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Subacute Cardiac Tamponade Due to Tuberculous Pericarditis Diagnosed by Urine Lipoarabinomannan Assay in a Immunocompetent Patient in Oyam District, Uganda: A Case Report

Author

Listed:
  • Elda De Vita

    (Clinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari, 70121 Bari, Italy
    These authors contributed equally to this work.)

  • Francesco Vladimiro Segala

    (Dipartimento di Sicurezza e Bioetica—Sezione di Malattie Infettive, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
    These authors contributed equally to this work.)

  • James Amone

    (St. John’s XXIII Hospital Aber, Jaber 21310, Uganda)

  • Kabuga Samuel

    (St. John’s XXIII Hospital Aber, Jaber 21310, Uganda)

  • Claudia Marotta

    (Doctors with Africa CUAMM, 35100 Padua, Italy)

  • Giovanni Putoto

    (Doctors with Africa CUAMM, 35100 Padua, Italy)

  • Ritah Nassali

    (St. John’s XXIII Hospital Aber, Jaber 21310, Uganda)

  • Peter Lochoro

    (Doctors with Africa CUAMM, Kampala 21310, Uganda)

  • Davide Fiore Bavaro

    (Clinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari, 70121 Bari, Italy)

  • Jerry Ictho

    (Doctors with Africa CUAMM, Kampala 21310, Uganda)

  • Samuel Okori

    (St. John’s XXIII Hospital Aber, Jaber 21310, Uganda)

  • Francesco Di Gennaro

    (Clinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari, 70121 Bari, Italy
    Doctors with Africa CUAMM, 35100 Padua, Italy)

  • Annalisa Saracino

    (Clinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari, 70121 Bari, Italy)

Abstract

Background: Uganda ranks among the countries with the highest burden of TB the world and tuberculous pericarditis (TBP) affects up to 2% of people diagnosed with pulmonary tuberculosis worldwide. In Africa, it represents the most common cause of pericardial disease. Here, we present the case of a 21-year-old male patient who was diagnosed of cardiac tamponade due to tuberculous pericarditis with a positive urine LF-LAM. Case report: We report a case of a 21-year-old male living in Oyam district, Uganda, who presented to the emergency department with difficulty in breathing, easy fatigability, general body weakness, and abdominal pain. A chest X-ray showed the presence of right pleural effusion and massive cardiomegaly. Thus, percutaneous pericardiocentesis was performed immediately and pericardial fluid resulted negative both for gram staining and real-time PCR test Xpert MTB/RIF. The following day’s urine LF-LAM test resulted positive, and antitubercular therapy started with gradual improvement. During the follow-up visits, the patient remained asymptomatic, reporting good compliance to the antitubercular therapy. Conclusion: Our case highlights the potential usefulness of a LF-LAM-based diagnostic approach, suggesting that, in low-resource settings, this test might be used as part of routine diagnostic workup in patients with pericardial disease or suspected extra-pulmonary tuberculosis.

Suggested Citation

  • Elda De Vita & Francesco Vladimiro Segala & James Amone & Kabuga Samuel & Claudia Marotta & Giovanni Putoto & Ritah Nassali & Peter Lochoro & Davide Fiore Bavaro & Jerry Ictho & Samuel Okori & Frances, 2022. "Subacute Cardiac Tamponade Due to Tuberculous Pericarditis Diagnosed by Urine Lipoarabinomannan Assay in a Immunocompetent Patient in Oyam District, Uganda: A Case Report," IJERPH, MDPI, vol. 19(22), pages 1-6, November.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:22:p:15143-:d:975030
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