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Persistent Depressive Disorder-Related Effect of Sleep Disorder on the Highest Risk of Suicide in Taiwan, 2000–2015

Author

Listed:
  • Sheng-Huang Hsiao

    (Department of Neurosurgery, Taipei City Hospital, Ren-Ai Branch, Taipei 10629, Taiwan
    Department of Psychology, National Chengchi University, Taipei 11605, Taiwan)

  • Chih-Chien Cheng

    (Department of Mechanical Engineering, National Central University, Jhongli 32001, Taiwan
    Department of Obstetrics/Gynecology, Taipei City Hospital, Taipei 10341, Taiwan
    School of Medicine, College of Medicine, Fu-Jen Catholic University, New Taipei City 242062, Taiwan)

  • Iau-Jin Lin

    (Department of Medical Research, Tri-Service General Hospital, Taipei 11490, Taiwan
    School of Public Health, National Defense Medical Center, Taipei 11490, Taiwan)

  • Chia-Peng Yu

    (Department of Medical Research, Tri-Service General Hospital, Taipei 11490, Taiwan
    School of Public Health, National Defense Medical Center, Taipei 11490, Taiwan)

  • Yao-Ching Huang

    (Department of Medical Research, Tri-Service General Hospital, Taipei 11490, Taiwan
    School of Public Health, National Defense Medical Center, Taipei 11490, Taiwan
    Department of Chemical Engineering and Biotechnology, National Taipei University of Technology (Taipei Tech), Taipei 10608, Taiwan)

  • Shi-Hao Huang

    (Department of Chemical Engineering and Biotechnology, National Taipei University of Technology (Taipei Tech), Taipei 10608, Taiwan)

  • Chien-An Sun

    (Department of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City 242062, Taiwan
    Big Data Center, College of Medicine, Fu-Jen Catholic University, New Taipei City 242062, Taiwan)

  • Li-Yun Fann

    (Department of Medical Research, Tri-Service General Hospital, Taipei 11490, Taiwan
    School of Public Health, National Defense Medical Center, Taipei 11490, Taiwan
    Department of Nursing, Taipei City Hospital, Taipei 10684, Taiwan
    Department of Nurse-Midwifery and Women Health, National Taipei University of Nursing and Health Sciences, Taipei 11220, Taiwan)

  • Miin-Yea Sheu

    (Department of Nursing, Taipei City Hospital, Taipei 10684, Taiwan)

  • Wu-Chien Chien

    (Department of Medical Research, Tri-Service General Hospital, Taipei 11490, Taiwan
    School of Public Health, National Defense Medical Center, Taipei 11490, Taiwan
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan
    Taiwanese Injury Prevention and Safety Promotion Association (TIPSPA), Taipei 11490, Taiwan)

Abstract

Objective: to investigate whether persistent depressive disorder (PDD) affects sleep disorders (SDs) and increased suicide risk. Methods: in this study, we used the National Health Insurance Research Database (NHIRD) to select 117,033 SD patients, of whom 137 died by suicide, and 468,132 non-SD patients, of whom 118 died by suicide, and analyzed gender, age, and co-existing diseases. Hazard ratios (HRs) and 95% confidence intervals (CI) were calculated using a multivariate Cox proportional hazards model. Results: the hazard ratio of suicide in SD patients was 1.429 times that of non-SD patients. The hazard ratio of suicide in female patients was 1.297 times higher than in males. Compared with people without PDD, people with PDD had a 7.195 times higher hazard ratio for suicide than those without PDD. PDD patients with SDs had a 2.05 times higher hazard ratio for suicide than those with no SDs. Conclusions: suicide risk was increased in SD patients, and the maximum suicide risk was greater in SD patients with PDD than in non-PDD patients. PDD affected SDs and increased suicide risk. Clinicians should be aware of the possibility that PDD affects patients with SDs and contributes to suicide risk.

Suggested Citation

  • Sheng-Huang Hsiao & Chih-Chien Cheng & Iau-Jin Lin & Chia-Peng Yu & Yao-Ching Huang & Shi-Hao Huang & Chien-An Sun & Li-Yun Fann & Miin-Yea Sheu & Wu-Chien Chien, 2022. "Persistent Depressive Disorder-Related Effect of Sleep Disorder on the Highest Risk of Suicide in Taiwan, 2000–2015," IJERPH, MDPI, vol. 19(20), pages 1-13, October.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:20:p:13169-:d:941038
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