Author
Listed:
- Yu-Lin Shih
(Department of Family Medicine, Chang-Gung Memorial Hospital, Linkou Branch, Taoyuan 33305, Taiwan
These authors contributed equally to this work.)
- Yueh Lin
(Department of Family Medicine, Chang-Gung Memorial Hospital, Linkou Branch, Taoyuan 33305, Taiwan)
- Jau-Yuan Chen
(Department of Family Medicine, Chang-Gung Memorial Hospital, Linkou Branch, Taoyuan 33305, Taiwan
College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
These authors contributed equally to this work.)
Abstract
Metabolic syndrome (MetS) has become the most important issue in family medicine and primary care because it is a cluster of metabolic abnormalities that are a burden on health care in many countries. Highly sensitive C-reactive protein (hsCRP), which is elevated in inflammatory situations, can be produced by monocyte-derived macrophages in adipose tissue. People with MetS tend to have more adipose tissue. Therefore, we aimed to investigate the association between hsCRP and MetS among elderly individuals aged 50 years and older in northern Taiwan. This study was a cross-sectional community-based study that included 400 middle-aged and elderly Taiwanese adults, and 400 participants were eligible for analysis. We divided the participants into a MetS group and a non-MetS group. Pearson’s correlations were calculated between hsCRP and other related risk factors. Furthermore, the relationship between hsCRP and MetS was analyzed with logistic regression. People in the MetS group were more likely to have higher hsCRP levels. The Pearson’s correlation analysis showed a positive correlation with hsCRP. In the logistic regression, hsCRP was significantly associated with MetS, even with the adjustment for BMI, uric acid, age, sex, smoking status, drinking status, hypertension, diabetes mellitus, and dyslipidemia. In summary, our research indicated that hsCRP could be an independent risk factor for MetS.
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