IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i19p12839-d935449.html
   My bibliography  Save this article

Sex-Specific Effect of Obesity on Epiblepharon in Different Age Groups: A Case-Control Study

Author

Listed:
  • Jin-Jhe Wang

    (Department of Ophthalmology, Chiayi Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
    Department of Ophthalmology, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan)

  • Chien-Hsiung Lai

    (Department of Ophthalmology, Chiayi Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
    Department of Ophthalmology, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
    Department of Nursing, Chang Gung University of Science and Technology, Chiayi 61363, Taiwan
    School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan)

  • Ting-Yu Kuo

    (Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan)

  • Meng-Hung Lin

    (Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan)

  • Yao-Hsu Yang

    (School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
    Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
    Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan)

  • Chau-Yin Chen

    (Department of Ophthalmology, Chiayi Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
    Department of Ophthalmology, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan)

Abstract

Obesity has been regarded as a risk factor for several ocular diseases. This study aims to investigate the age- and sex-specific relationship between epiblepharon and obesity in children. A retrospective case–control study was conducted using the Chang Gung Research Database. Children ≤ 18 years of age with epiblepharon were identified from 1 January 2009 to 31 December 2019. Children were classified into three groups: normal, overweight and obese groups. A total of 513 patients and 1026 controls (57.7% males) aged 1 to 18 matched by sex and age were included in the analysis. The median body mass index (BMI) of children with epiblepharon was significantly higher than that of children without epiblepharon ( p < 0.001). In the subgroup analysis, among boys aged 4 to 9 years, the BMI in boys with epiblepharon was significantly higher than that in boys without epiblepharon ( p < 0.05) and the risk of epiblepahron in overweight/obese boys was significantly higher than in non-overweight boys (OR = 1.74, 95% CI = 1.07–2.82 for age 4 to 6; OR = 3.06, 95% CI = 1.56–6.03 for age 7 to 9). On the other hand, among girls aged 13 to 18 years, the BMI in adolescent girls with epiblepharon was significantly higher than that in the control group ( p < 0.05) and overweight/obese girls had a statistically higher risk of persistent epiblepharon than non-overweight girls (OR = 3.70, 95% CI = 1.38–9.97). The association between obesity and epiblepharon varies in strength according to age in a sex-specific manner.

Suggested Citation

  • Jin-Jhe Wang & Chien-Hsiung Lai & Ting-Yu Kuo & Meng-Hung Lin & Yao-Hsu Yang & Chau-Yin Chen, 2022. "Sex-Specific Effect of Obesity on Epiblepharon in Different Age Groups: A Case-Control Study," IJERPH, MDPI, vol. 19(19), pages 1-9, October.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12839-:d:935449
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/19/12839/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/19/12839/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12839-:d:935449. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.