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Mediterranean Diet and Its Association with Cardiovascular Disease Risk Factors: A Scoping Review

Author

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  • Leigh Ann Richardson

    (Department of Epidemiology and Biostatistics, University of Nevada at Las Vegas, Las Vegas, NV 89154, USA)

  • Kenneth Izuora

    (Section of Endocrinology, Department of Internal Medicine, University of Nevada at Las Vegas, Las Vegas, NV 89102, USA)

  • Arpita Basu

    (Department of Kinesiology and Nutrition Sciences, School of Integrated Health Sciences, University of Nevada at Las Vegas, Las Vegas, NV 89154, USA)

Abstract

Atherosclerosis is the underlying cause of cardiovascular diseases (CVD) and is interrelated to stroke, heart attack, and heart failure. The Mediterranean Diet (MedDiet) has been closely associated with reduced CVD morbidity and mortality, but research is not well explored for this relationship in individuals with diabetes (who experience greater CVD morbidity and mortality than individuals without diabetes). The aim of this review was to explore the literature related to the MedDiet and atherosclerosis and associated risk factors in individuals with and without diabetes. In total, 570 articles were identified, and 36 articles were included. The articles were published between 2011 and 2021. Platforms used for the search were PubMed, Scopus, Cochrane Library, and ProQuest. Our literature search included clinical and observational studies. Clinical studies revealed the MedDiet was associated with improved biomarkers, plaque, and anthropometric measurements that are associated with atherosclerosis and CVD. Observational studies identified associations between the MedDiet and lower presence of atherosclerosis, improved vascular aging, and increased endothelial progenitor cells. However, most of the studies took place in Mediterranean countries. Further research is needed to better understand the long-term effects the MedDiet on atherosclerosis and its associated risk factors in diverse populations to include individuals with and without diabetes.

Suggested Citation

  • Leigh Ann Richardson & Kenneth Izuora & Arpita Basu, 2022. "Mediterranean Diet and Its Association with Cardiovascular Disease Risk Factors: A Scoping Review," IJERPH, MDPI, vol. 19(19), pages 1-30, October.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12762-:d:934378
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    References listed on IDEAS

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    1. Elena M Yubero-Serrano & Carolina Fernandez-Gandara & Antonio Garcia-Rios & Oriol A Rangel-Zuñiga & Francisco M Gutierrez-Mariscal & Jose D Torres-Peña & Carmen Marin & Javier Lopez-Moreno & Justo P C, 2020. "Mediterranean diet and endothelial function in patients with coronary heart disease: An analysis of the CORDIOPREV randomized controlled trial," PLOS Medicine, Public Library of Science, vol. 17(9), pages 1-28, September.
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