IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i19p12170-d925139.html
   My bibliography  Save this article

A Pilot Study on the Concentration, Distribution and Bioaccumulation of Polybrominated Diphenyl Ethers (PBDEs) in Tissues and Organs of Grassland Sheep

Author

Listed:
  • Wenming Chen

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Xinrui Yang

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Junsong Bao

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Ziyi Lin

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Tianwei Li

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Ying Wang

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Aiqin Zhang

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Jicheng Hu

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China)

  • Jun Jin

    (College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China
    Beijing Food and Environmental Health Engineering Center, Beijing 100081, China)

Abstract

Polybrominated diphenyl ether (PBDE) concentrations in various tissues and organs of grassland sheep from Inner Mongolia, China, were determined. The abilities of PBDEs binding to ovine serum albumin (OSA) and Cytochrome P450 enzyme (CYP3A24) were assessed by fluorescence spectroscopy and molecular docking simulations. The PBDE concentrations in the sheep tissue and organ samples were 33.4–167 pg/g dw. The distribution of PBDEs in sheep organs and tissues is affected not only by the function of organs and tissues, but also by the characteristics of PBDEs. Adipose tissue tends to bioaccumulate more-brominated BDEs (BDE-154, -153, and -183), but muscle tissues and visceral organs mainly bioaccumulate less-brominated BDEs. The distribution of PBDEs in visceral organs is mainly affected by the transport of ovine serum albumin (OSA) and the metabolism of CYP3A24 enzyme. The distribution of PBDEs in adipose tissue and brain is mainly affected by their logK OW .

Suggested Citation

  • Wenming Chen & Xinrui Yang & Junsong Bao & Ziyi Lin & Tianwei Li & Ying Wang & Aiqin Zhang & Jicheng Hu & Jun Jin, 2022. "A Pilot Study on the Concentration, Distribution and Bioaccumulation of Polybrominated Diphenyl Ethers (PBDEs) in Tissues and Organs of Grassland Sheep," IJERPH, MDPI, vol. 19(19), pages 1-13, September.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12170-:d:925139
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/19/12170/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/19/12170/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12170-:d:925139. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.