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Association between Bone-Related Physiological Substances and Oral Function in Community-Dwelling Older People

Author

Listed:
  • Misa Nakamura

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan
    Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

  • Masakazu Imaoka

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan
    Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

  • Fumie Tazaki

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan
    Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

  • Hidetoshi Nakao

    (Department of Physical Therapy, Josai International University, Tougane 283-0002, Chiba, Japan)

  • Mitsumasa Hida

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan
    Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

  • Ryohei Kono

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan
    Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

  • Hideki Kanemoto

    (Department of Psychiatry, Graduate School of Medicine, Osaka University, Suita 565-0871, Osaka, Japan)

  • Masatoshi Takeda

    (Cognitive Reserve Research Center, Osaka Kawasaki Rehabilitation University, Kaizuka 597-0104, Osaka, Japan)

Abstract

Background: Oral dysfunction is related to long-term cares including activities of daily living. The objective of this study was to determine the association between oral function and the bone-related physiological substances osteocalcin (OC) and insulin-like growth factor-1 (IGF-1). Methods: The study participants were 139 community-dwelling older people in Japan. Evaluation of oral dysfunction was based on subjective judgment by each participant. Blood analysis included OC, IGF-1, and albumin. Results: Univariate and multiple logistic analyses showed that IGF-1 was significantly associated with a “decline in masticatory function” ( p = 0.0074 and p = 0.0308, respectively). Receiver operating characteristic curve analysis of IGF-1 levels revealed a threshold score of 108 ng/mL ( p < 0.01) for discriminating a “decline in masticatory function”. Logistic regression analysis revealed that participants with an IGF-1 level ≤108 ng/mL had an odds ratio of 4.31 ( p < 0.05) for a “decline in masticatory function”. No significant association was found between the OC level and oral dysfunction. Conclusions: These results suggest a possible relationship between lower serum IGF-1 levels and a decline in masticatory dysfunction in community-dwelling older people.

Suggested Citation

  • Misa Nakamura & Masakazu Imaoka & Fumie Tazaki & Hidetoshi Nakao & Mitsumasa Hida & Ryohei Kono & Hideki Kanemoto & Masatoshi Takeda, 2022. "Association between Bone-Related Physiological Substances and Oral Function in Community-Dwelling Older People," IJERPH, MDPI, vol. 19(17), pages 1-8, August.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:17:p:10677-:d:899193
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